node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKO96084.1 | AKO96389.1 | MALG_00890 | MALG_01202 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Cobalt-precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.670 |
AKO96084.1 | AKO96390.1 | MALG_00890 | MALG_01203 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Cobalamin synthesis G. | 0.557 |
AKO96084.1 | AKO96391.1 | MALG_00890 | MALG_01204 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Decarboxylating; CbiE subunit/precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit. | 0.845 |
AKO96084.1 | AKO96393.1 | MALG_00890 | MALG_01206 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Cobalt-precorrin-3B C17-methyltransferase. | 0.621 |
AKO96084.1 | AKO96394.1 | MALG_00890 | MALG_01207 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Cobalt-precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.948 |
AKO96084.1 | AKO96395.1 | MALG_00890 | MALG_01208 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Cobalt-Precorrin isomerase. | 0.569 |
AKO96084.1 | AKO96396.1 | MALG_00890 | MALG_01209 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Cobalamin biosynthesis protein CobG; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.895 |
AKO96084.1 | AKO96397.1 | MALG_00890 | MALG_01210 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Cobalamin biosynthesis protein CobN; And related Mg-chelatases. | 0.507 |
AKO96084.1 | AKO97462.1 | MALG_00890 | MALG_02298 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.990 |
AKO96389.1 | AKO96084.1 | MALG_01202 | MALG_00890 | Cobalt-precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.670 |
AKO96389.1 | AKO96390.1 | MALG_01202 | MALG_01203 | Cobalt-precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. | Cobalamin synthesis G. | 0.998 |
AKO96389.1 | AKO96391.1 | MALG_01202 | MALG_01204 | Cobalt-precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. | Decarboxylating; CbiE subunit/precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit. | 0.998 |
AKO96389.1 | AKO96393.1 | MALG_01202 | MALG_01206 | Cobalt-precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. | Cobalt-precorrin-3B C17-methyltransferase. | 0.999 |
AKO96389.1 | AKO96394.1 | MALG_01202 | MALG_01207 | Cobalt-precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. | Cobalt-precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.981 |
AKO96389.1 | AKO96395.1 | MALG_01202 | MALG_01208 | Cobalt-precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. | Cobalt-Precorrin isomerase. | 0.984 |
AKO96389.1 | AKO96396.1 | MALG_01202 | MALG_01209 | Cobalt-precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. | Cobalamin biosynthesis protein CobG; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.536 |
AKO96389.1 | AKO96397.1 | MALG_01202 | MALG_01210 | Cobalt-precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. | Cobalamin biosynthesis protein CobN; And related Mg-chelatases. | 0.811 |
AKO96389.1 | AKO97462.1 | MALG_01202 | MALG_02298 | Cobalt-precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.668 |
AKO96390.1 | AKO96084.1 | MALG_01203 | MALG_00890 | Cobalamin synthesis G. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.557 |
AKO96390.1 | AKO96389.1 | MALG_01203 | MALG_01202 | Cobalamin synthesis G. | Cobalt-precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.998 |