STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dinB_1DNA polymerase-4; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (432 aa)    
Predicted Functional Partners:
SER73809.1
PhoP regulatory network protein YrbL.
   
 0.994
hrpB
ATP-dependent helicase HrpB.
    
 0.992
SER94799.1
Hypothetical protein.
  
 0.991
dnaN_1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.987
dnaN_2
DNA polymerase-3 subunit beta.
   
 0.987
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
 0.986
rhlE_2
ATP-dependent RNA helicase RhlE.
   
 0.975
rhlE_1
ATP-dependent RNA helicase RhlE.
   
 0.975
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.975
rhlE_3
Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family.
   
 0.975
Your Current Organism:
Pseudovibrio axinellae
NCBI taxonomy Id: 989403
Other names: DSM 24994, NCIMB 14761, P. axinellae, Pseudovibrio sp. Ad2, strain Ad2
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