STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
grxAGlutaredoxin; Protein involved in thiol-disulfide exchange intermediate activity. (87 aa)    
Predicted Functional Partners:
MCON_0019
Conserved hypothetical protein.
 
  
 0.950
MCON_1654
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 0.887
msrAB
Peptide methionine sulfoxide reductase MsrB/MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.870
MCON_0018
Copper-translocating P-type ATPase; Protein involved in copper-exporting ATPase activity, copper ion transporter activity and copper ion transport.
   
 
 0.723
MCON_0017
YHS domain protein; Protein involved in metal ion binding.
       0.627
cobA
Uroporphyrinogen III synthase/methyltransferase; Protein involved in uroporphyrin-III C-methyltransferase activity and siroheme biosynthetic process.
  
  
 0.577
MCON_3422
HesB/YadR/YfhF-family protein.
  
  
 0.541
MCON_3047
Cytochrome c biogenesis protein, transmembrane region.
     
 0.484
nadE
Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
 
 0.478
MCON_0021
Conserved hypothetical protein.
       0.434
Your Current Organism:
Methanothrix soehngenii
NCBI taxonomy Id: 990316
Other names: M. soehngenii GP6, Methanosaeta concilii DSM 3671, Methanosaeta concilii GP6, Methanothrix soehngenii DSM 3671, Methanothrix soehngenii GP6
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.