STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCON_0567Conserved hypothetical protein TIGR00303; Belongs to the UPF0284 family. (346 aa)    
Predicted Functional Partners:
cobA
Uroporphyrinogen III synthase/methyltransferase; Protein involved in uroporphyrin-III C-methyltransferase activity and siroheme biosynthetic process.
  
  
 0.866
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.761
MCON_0566
Alcohol dehydrogenase, zinc-containing.
     
 0.749
hisC
Protein involved in histidinol-phosphate transaminase activity.
  
  
 0.727
cbiG
Cobalamin (vitamin B12) biosynthesis CbiG protein.
  
  
 0.710
MCON_1722
Conserved hypothetical protein.
 
     0.693
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.669
cobD
Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.656
MCON_1684
uroporphyrin-III C/tetrapyrrole methyltransferase; Protein involved in precorrin-2 C20-methyltransferase activity; Belongs to the precorrin methyltransferase family.
 
  
 0.623
MCON_1685
Conserved hypothetical protein.
 
  
 0.619
Your Current Organism:
Methanothrix soehngenii
NCBI taxonomy Id: 990316
Other names: M. soehngenii GP6, Methanosaeta concilii DSM 3671, Methanosaeta concilii GP6, Methanothrix soehngenii DSM 3671, Methanothrix soehngenii GP6
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