STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
asdProtein involved in aspartate-semialdehyde dehydrogenase activity. (342 aa)    
Predicted Functional Partners:
MCON_1651
Aspartate kinase, monofunctional class; Protein involved in aspartate kinase activity; Belongs to the aspartokinase family.
 
 0.999
hdh
Protein involved in homoserine dehydrogenase activity and aspartate family amino acid biosynthetic process.
 
 0.984
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
 
 0.975
ectB
Diaminobutyrate--2-oxoglutarate aminotransferase; Protein involved in diaminobutyrate-2-oxoglutarate transaminase activity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
    
 0.931
MCON_1339
4Fe-4S ferredoxin, iron-sulfur binding domain protein.
    
  0.917
MCON_1340
Domain of unknown function DUF39/CBS domain fusion protein.
    
  0.917
mscL
Large conductance mechanosensitive channel protein.
     
 0.865
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine.
  
  
 0.833
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
 0.830
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
  
 0.787
Your Current Organism:
Methanothrix soehngenii
NCBI taxonomy Id: 990316
Other names: M. soehngenii GP6, Methanosaeta concilii DSM 3671, Methanosaeta concilii GP6, Methanothrix soehngenii DSM 3671, Methanothrix soehngenii GP6
Server load: low (20%) [HD]