STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbiK-2Cobalt chelatase. (299 aa)    
Predicted Functional Partners:
MCON_1503
Siroheme synthase domain protein; Protein involved in precorrin-2 dehydrogenase activity and sirohydrochlorin ferrochelatase activity.
  
 
 0.958
MCON_1684
uroporphyrin-III C/tetrapyrrole methyltransferase; Protein involved in precorrin-2 C20-methyltransferase activity; Belongs to the precorrin methyltransferase family.
 
  
 0.948
cbiK
Cobalt chelatase.
  
  
 
0.907
cbiX
Sirohydrochlorin cobaltochelatase; Protein involved in cobalt ion binding.
     
  0.900
cobA
Uroporphyrinogen III synthase/methyltransferase; Protein involved in uroporphyrin-III C-methyltransferase activity and siroheme biosynthetic process.
  
 0.892
cobM
Protein involved in precorrin-4 C11-methyltransferase activity; Belongs to the precorrin methyltransferase family.
   
 0.695
cobB2
Cobyrinic Acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
 
  
 0.677
MCON_2897
Alkylhydroperoxidase like protein, AhpD family.
       0.647
MCON_1681
cobalt-precorrin-3B C(17)-methyltransferase; Protein involved in S-adenosylmethionine-dependent methyltransferase activity.
 
   
 0.633
cbiD
Putative cobalt-precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
   
 0.608
Your Current Organism:
Methanothrix soehngenii
NCBI taxonomy Id: 990316
Other names: M. soehngenii GP6, Methanosaeta concilii DSM 3671, Methanosaeta concilii GP6, Methanothrix soehngenii DSM 3671, Methanothrix soehngenii GP6
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