STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDM68378.1Thiopurine S-methyltransferase (TPMT). (205 aa)    
Predicted Functional Partners:
SDM68402.1
Hypothetical protein.
       0.791
SDN01139.1
Amino acid adenylation domain-containing protein.
    
 0.703
SDN01167.1
Amino acid adenylation domain-containing protein.
    
 0.703
SDL66335.1
methylmalonyl-CoA/ethylmalonyl-CoA epimerase.
 
      0.636
SDN01108.1
Amino acid adenylation domain-containing protein.
    
 0.618
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.561
SDM93659.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
    
 0.540
SDM68440.1
Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family.
       0.519
SDL88829.1
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.516
SDM68291.1
Hydroxyacylglutathione hydrolase.
       0.496
Your Current Organism:
Pedobacter ruber
NCBI taxonomy Id: 990371
Other names: DSM 24536, LMG 26240, LMG:26240, P. ruber, Pedobacter ruber Margesin and Zhang 2013, Pedobacter sp. W1, strain W1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.