STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ilvAL-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (401 aa)    
Predicted Functional Partners:
SDK99094.1
Acetolactate synthase, small subunit.
  
 
 0.900
SDK53489.1
Threonine synthase.
  
 
 0.895
SDK99119.1
Acetolactate synthase, large subunit.
 
  0.768
trpB
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
 0.726
SDK26878.1
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.716
SDK39157.1
Branched-chain amino acid aminotransferase.
  
 
 0.680
SDK93689.1
5-methyltetrahydrofolate--homocysteine methyltransferase.
  
 0.675
SDK51682.1
L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.662
trpA
Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
   
 
 0.657
SDK74080.1
Glyoxylate/hydroxypyruvate reductase A.
   
 
  0.649
Your Current Organism:
Albidovulum xiamenense
NCBI taxonomy Id: 990712
Other names: A. xiamenense, Albidovulum sp. YBY-7, Albidovulum xiamenense Yin et al. 2012, CGMCC 1.10789, LMG 26247, LMG:26247, MCCC 1A06317, strain YBY-7
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