STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDK61125.1uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (275 aa)    
Predicted Functional Partners:
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.992
cysC
Sulfate adenylyltransferase; Catalyzes the synthesis of activated sulfate.
  
  
 0.979
cysG
uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
 
 
0.969
SDJ92809.1
Precorrin-2/cobalt-factor-2 C20-methyltransferase.
 
 
0.946
SDK75042.1
cob(II)yrinic acid a,c-diamide reductase.
   
 0.930
SDJ92912.1
Sirohydrochlorin cobaltochelatase.
 
 
 0.924
SDK84226.1
Sulfite reductase (NADPH) hemoprotein beta-component; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.917
SDK82858.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.913
SDK84195.1
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
  
 0.894
SDK60955.1
Heme d1 biosynthesis radical SAM protein NirJ.
  
 0.889
Your Current Organism:
Albidovulum xiamenense
NCBI taxonomy Id: 990712
Other names: A. xiamenense, Albidovulum sp. YBY-7, Albidovulum xiamenense Yin et al. 2012, CGMCC 1.10789, LMG 26247, LMG:26247, MCCC 1A06317, strain YBY-7
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