node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTL6A | ACTR6 | ENSBTAP00000037066 | ENSBTAP00000018384 | Actin-like protein 6B; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex), as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion, and is required for postmitotic neural development and dendritic outgrowth. [...] | Actin related protein 6; Belongs to the actin family. | 0.537 |
ACTL6A | CFDP1 | ENSBTAP00000037066 | ENSBTAP00000069228 | Actin-like protein 6B; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex), as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion, and is required for postmitotic neural development and dendritic outgrowth. [...] | Craniofacial development protein 1; May play a role during embryogenesis. | 0.616 |
ACTL6A | DMAP1 | ENSBTAP00000037066 | ENSBTAP00000007766 | Actin-like protein 6B; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex), as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion, and is required for postmitotic neural development and dendritic outgrowth. [...] | DNA methyltransferase 1 associated protein 1. | 0.945 |
ACTL6A | EP400 | ENSBTAP00000037066 | ENSBTAP00000027216 | Actin-like protein 6B; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex), as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion, and is required for postmitotic neural development and dendritic outgrowth. [...] | E1A binding protein p400. | 0.894 |
ACTL6A | G3N326_BOVIN | ENSBTAP00000037066 | ENSBTAP00000056298 | Actin-like protein 6B; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex), as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion, and is required for postmitotic neural development and dendritic outgrowth. [...] | Uncharacterized protein. | 0.828 |
ACTL6A | RUVBL1 | ENSBTAP00000037066 | ENSBTAP00000027964 | Actin-like protein 6B; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex), as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion, and is required for postmitotic neural development and dendritic outgrowth. [...] | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | 0.976 |
ACTL6A | RUVBL2 | ENSBTAP00000037066 | ENSBTAP00000031853 | Actin-like protein 6B; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex), as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion, and is required for postmitotic neural development and dendritic outgrowth. [...] | RuvB-like 2; Possesses single-stranded DNA-stimulated ATPase and ATP- dependent DNA helicase (5' to 3') activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits in the ring- like structure contribute to the ATPase activity (By similarity). Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A (By similarity). This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with oth [...] | 0.937 |
ACTL6A | VPS72 | ENSBTAP00000037066 | ENSBTAP00000024063 | Actin-like protein 6B; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex), as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion, and is required for postmitotic neural development and dendritic outgrowth. [...] | Vacuolar protein sorting-associated protein 72 homolog; Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. | 0.815 |
ACTL6A | ZNHIT1 | ENSBTAP00000037066 | ENSBTAP00000060443 | Actin-like protein 6B; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex), as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion, and is required for postmitotic neural development and dendritic outgrowth. [...] | Zinc finger HIT domain-containing protein 1; Seems to play a role in p53-mediated apoptosis induction (By similarity). Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity (By similarity); Belongs to the ZNHIT1 family. | 0.746 |
ACTR6 | ACTL6A | ENSBTAP00000018384 | ENSBTAP00000037066 | Actin related protein 6; Belongs to the actin family. | Actin-like protein 6B; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex), as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion, and is required for postmitotic neural development and dendritic outgrowth. [...] | 0.537 |
ACTR6 | CFDP1 | ENSBTAP00000018384 | ENSBTAP00000069228 | Actin related protein 6; Belongs to the actin family. | Craniofacial development protein 1; May play a role during embryogenesis. | 0.755 |
ACTR6 | DMAP1 | ENSBTAP00000018384 | ENSBTAP00000007766 | Actin related protein 6; Belongs to the actin family. | DNA methyltransferase 1 associated protein 1. | 0.920 |
ACTR6 | EP400 | ENSBTAP00000018384 | ENSBTAP00000027216 | Actin related protein 6; Belongs to the actin family. | E1A binding protein p400. | 0.860 |
ACTR6 | G3N326_BOVIN | ENSBTAP00000018384 | ENSBTAP00000056298 | Actin related protein 6; Belongs to the actin family. | Uncharacterized protein. | 0.916 |
ACTR6 | RUVBL1 | ENSBTAP00000018384 | ENSBTAP00000027964 | Actin related protein 6; Belongs to the actin family. | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | 0.937 |
ACTR6 | RUVBL2 | ENSBTAP00000018384 | ENSBTAP00000031853 | Actin related protein 6; Belongs to the actin family. | RuvB-like 2; Possesses single-stranded DNA-stimulated ATPase and ATP- dependent DNA helicase (5' to 3') activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits in the ring- like structure contribute to the ATPase activity (By similarity). Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A (By similarity). This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with oth [...] | 0.943 |
ACTR6 | VPS72 | ENSBTAP00000018384 | ENSBTAP00000024063 | Actin related protein 6; Belongs to the actin family. | Vacuolar protein sorting-associated protein 72 homolog; Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. | 0.742 |
ACTR6 | ZNHIT1 | ENSBTAP00000018384 | ENSBTAP00000060443 | Actin related protein 6; Belongs to the actin family. | Zinc finger HIT domain-containing protein 1; Seems to play a role in p53-mediated apoptosis induction (By similarity). Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity (By similarity); Belongs to the ZNHIT1 family. | 0.852 |
CFDP1 | ACTL6A | ENSBTAP00000069228 | ENSBTAP00000037066 | Craniofacial development protein 1; May play a role during embryogenesis. | Actin-like protein 6B; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex), as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion, and is required for postmitotic neural development and dendritic outgrowth. [...] | 0.616 |
CFDP1 | ACTR6 | ENSBTAP00000069228 | ENSBTAP00000018384 | Craniofacial development protein 1; May play a role during embryogenesis. | Actin related protein 6; Belongs to the actin family. | 0.755 |