STRINGSTRING
NXN protein (Bos taurus) - STRING interaction network
"NXN" - Nucleoredoxin in Bos taurus
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
NXNNucleoredoxin; Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity); Belongs to the nucleoredoxin family (435 aa)    
Predicted Functional Partners:
TXNDC2
Uncharacterized protein; Thioredoxin domain containing 2 (spermatozoa) (515 aa)
           
  0.664
TMEM44
TMEM44 protein; Bos taurus transmembrane protein 44 (TMEM44), mRNA (445 aa)
           
  0.658
SSLP1
Bos taurus secreted seminal-vesicle Ly-6 protein 1 (SSLP1), mRNA (100 aa)
           
  0.636
TXN
Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status [...] (97 aa)
           
  0.634
TXNDC8
Bos taurus thioredoxin domain containing 8 (spermatozoa) (TXNDC8), mRNA; Belongs to the thioredoxin family (105 aa)
           
  0.609
LYNX1
Ly-6/neurotoxin-like protein 1; Acts in different tissues through interaction to nicotinic acetylcholine receptors (nAChRs). The proposed role as modulator of nAChR activity seems to be dependent on the nAChR subtype and stoichiometry, and to involve an effect on nAChR trafficking and its cell surface expression, and on single channel properties of the nAChR inserted in the plasma membrane.Modulates functional properties of nicotinic acetylcholine receptors (nAChRs) to prevent excessive excitation, and hence neurodegeneration. Enhances desensitization by increasing both the rate and ex [...] (116 aa)
           
  0.598
ZXDC
ZXD family zinc finger C (760 aa)
           
  0.584
JAKMIP2
Janus kinase and microtubule interacting protein 2 (820 aa)
           
  0.559
CNTNAP1
Contactin associated protein 1 (1388 aa)
           
  0.549
LARS
Bos taurus leucyl-tRNA synthetase (LARS), mRNA; Belongs to the class-I aminoacyl-tRNA synthetase family (1176 aa)
     
   
  0.547
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bos taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, domestic cattle, domestic cow
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