node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDC5L | DDX46 | ENSBTAP00000026654 | ENSBTAP00000074561 | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Belongs to the CEF1 family. | DEAD-box helicase 46. | 0.718 |
CDC5L | PRPF40A | ENSBTAP00000026654 | ENSBTAP00000054353 | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Belongs to the CEF1 family. | Pre-mRNA processing factor 40 homolog A. | 0.713 |
CDC5L | PRPF40B | ENSBTAP00000026654 | ENSBTAP00000057567 | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Belongs to the CEF1 family. | Pre-mRNA processing factor 40 homolog B. | 0.960 |
CDC5L | RBM39 | ENSBTAP00000026654 | ENSBTAP00000060007 | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Belongs to the CEF1 family. | RNA binding motif protein 39. | 0.841 |
CDC5L | SF1 | ENSBTAP00000026654 | ENSBTAP00000001376 | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Belongs to the CEF1 family. | Splicing factor 1. | 0.966 |
CDC5L | SF3A1 | ENSBTAP00000026654 | ENSBTAP00000004398 | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Belongs to the CEF1 family. | Splicing factor 3A subunit 1; Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes. | 0.981 |
CDC5L | SF3A2 | ENSBTAP00000026654 | ENSBTAP00000062091 | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Belongs to the CEF1 family. | Splicing factor 3A subunit 2; Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes, including the Bact complex. Interacts directly with the duplex formed by U2 snRNA and the intron. | 0.975 |
CDC5L | SF3A3 | ENSBTAP00000026654 | ENSBTAP00000065151 | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Belongs to the CEF1 family. | Splicing factor 3a, subunit 3, 60kDa. | 0.987 |
CDC5L | U2AF2 | ENSBTAP00000026654 | ENSBTAP00000063486 | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Belongs to the CEF1 family. | U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. | 0.990 |
DDX46 | CDC5L | ENSBTAP00000074561 | ENSBTAP00000026654 | DEAD-box helicase 46. | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Belongs to the CEF1 family. | 0.718 |
DDX46 | PRPF40A | ENSBTAP00000074561 | ENSBTAP00000054353 | DEAD-box helicase 46. | Pre-mRNA processing factor 40 homolog A. | 0.689 |
DDX46 | PRPF40B | ENSBTAP00000074561 | ENSBTAP00000057567 | DEAD-box helicase 46. | Pre-mRNA processing factor 40 homolog B. | 0.834 |
DDX46 | RBM25 | ENSBTAP00000074561 | ENSBTAP00000022826 | DEAD-box helicase 46. | RNA binding motif protein 25. | 0.955 |
DDX46 | RBM39 | ENSBTAP00000074561 | ENSBTAP00000060007 | DEAD-box helicase 46. | RNA binding motif protein 39. | 0.601 |
DDX46 | SF1 | ENSBTAP00000074561 | ENSBTAP00000001376 | DEAD-box helicase 46. | Splicing factor 1. | 0.964 |
DDX46 | SF3A1 | ENSBTAP00000074561 | ENSBTAP00000004398 | DEAD-box helicase 46. | Splicing factor 3A subunit 1; Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes. | 0.989 |
DDX46 | SF3A2 | ENSBTAP00000074561 | ENSBTAP00000062091 | DEAD-box helicase 46. | Splicing factor 3A subunit 2; Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes, including the Bact complex. Interacts directly with the duplex formed by U2 snRNA and the intron. | 0.991 |
DDX46 | SF3A3 | ENSBTAP00000074561 | ENSBTAP00000065151 | DEAD-box helicase 46. | Splicing factor 3a, subunit 3, 60kDa. | 0.989 |
DDX46 | U2AF2 | ENSBTAP00000074561 | ENSBTAP00000063486 | DEAD-box helicase 46. | U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. | 0.701 |
PRPF40A | CDC5L | ENSBTAP00000054353 | ENSBTAP00000026654 | Pre-mRNA processing factor 40 homolog A. | Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Belongs to the CEF1 family. | 0.713 |