node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACAD9 | ECSIT | ENSBTAP00000073649 | ENSBTAP00000020029 | Acyl-CoA dehydrogenase family member 9. | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity); Belongs to the ECSIT family. | 0.999 |
ACAD9 | NDUFAF1 | ENSBTAP00000073649 | ENSBTAP00000067081 | Acyl-CoA dehydrogenase family member 9. | NADH:ubiquinone oxidoreductase complex assembly factor 1. | 0.999 |
ACAD9 | NDUFAF2 | ENSBTAP00000073649 | ENSBTAP00000028793 | Acyl-CoA dehydrogenase family member 9. | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2; Acts as a molecular chaperone for mitochondrial complex I assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.854 |
ACAD9 | NDUFAF5 | ENSBTAP00000073649 | ENSBTAP00000005639 | Acyl-CoA dehydrogenase family member 9. | NADH:ubiquinone oxidoreductase complex assembly factor 5. | 0.904 |
ACAD9 | NDUFAF6 | ENSBTAP00000073649 | ENSBTAP00000009959 | Acyl-CoA dehydrogenase family member 9. | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6; Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) at early stages. May play a role in the biogenesis of MT-ND1; Belongs to the NDUFAF6 family. | 0.854 |
ACAD9 | NDUFAF7 | ENSBTAP00000073649 | ENSBTAP00000001470 | Acyl-CoA dehydrogenase family member 9. | Protein arginine methyltransferase NDUFAF7, mitochondrial; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Acts by mediating symmetric dimethylation of 'Arg-118' of NDUFS2 after it assembles into the complex I, stabilizing the early intermediate complex. | 0.827 |
ACAD9 | NDUFS2 | ENSBTAP00000073649 | ENSBTAP00000002852 | Acyl-CoA dehydrogenase family member 9. | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.983 |
ACAD9 | NDUFS7 | ENSBTAP00000073649 | ENSBTAP00000051744 | Acyl-CoA dehydrogenase family member 9. | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.983 |
ACAD9 | NUBPL | ENSBTAP00000073649 | ENSBTAP00000053647 | Acyl-CoA dehydrogenase family member 9. | Nucleotide binding protein like. | 0.653 |
ACAD9 | TMEM126B | ENSBTAP00000073649 | ENSBTAP00000027441 | Acyl-CoA dehydrogenase family member 9. | Transmembrane protein 126B. | 0.999 |
ECSIT | ACAD9 | ENSBTAP00000020029 | ENSBTAP00000073649 | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity); Belongs to the ECSIT family. | Acyl-CoA dehydrogenase family member 9. | 0.999 |
ECSIT | NDUFAF1 | ENSBTAP00000020029 | ENSBTAP00000067081 | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity); Belongs to the ECSIT family. | NADH:ubiquinone oxidoreductase complex assembly factor 1. | 0.999 |
ECSIT | NDUFAF2 | ENSBTAP00000020029 | ENSBTAP00000028793 | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity); Belongs to the ECSIT family. | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2; Acts as a molecular chaperone for mitochondrial complex I assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.832 |
ECSIT | NDUFAF5 | ENSBTAP00000020029 | ENSBTAP00000005639 | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity); Belongs to the ECSIT family. | NADH:ubiquinone oxidoreductase complex assembly factor 5. | 0.848 |
ECSIT | NDUFAF6 | ENSBTAP00000020029 | ENSBTAP00000009959 | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity); Belongs to the ECSIT family. | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6; Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) at early stages. May play a role in the biogenesis of MT-ND1; Belongs to the NDUFAF6 family. | 0.832 |
ECSIT | NDUFAF7 | ENSBTAP00000020029 | ENSBTAP00000001470 | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity); Belongs to the ECSIT family. | Protein arginine methyltransferase NDUFAF7, mitochondrial; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Acts by mediating symmetric dimethylation of 'Arg-118' of NDUFS2 after it assembles into the complex I, stabilizing the early intermediate complex. | 0.839 |
ECSIT | NDUFS2 | ENSBTAP00000020029 | ENSBTAP00000002852 | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity); Belongs to the ECSIT family. | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.989 |
ECSIT | NDUFS7 | ENSBTAP00000020029 | ENSBTAP00000051744 | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity); Belongs to the ECSIT family. | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.953 |
ECSIT | NUBPL | ENSBTAP00000020029 | ENSBTAP00000053647 | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity); Belongs to the ECSIT family. | Nucleotide binding protein like. | 0.627 |
ECSIT | TMEM126B | ENSBTAP00000020029 | ENSBTAP00000027441 | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity); Belongs to the ECSIT family. | Transmembrane protein 126B. | 0.999 |