STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRN1Leucine-rich repeat neuronal protein 1 precursor; Bos taurus leucine rich repeat neuronal 1 (LRRN1), mRNA (716 aa)    
Predicted Functional Partners:
LRRC1
Leucine-rich repeat-containing protein 1; Bos taurus leucine rich repeat containing 1 (LRRC1), mRNA
      
 0.827
LRRC2
Leucine-rich repeat-containing protein 2; Bos taurus leucine rich repeat containing 2 (LRRC2), mRNA
      
 0.796
CACHD1
Vwfa and cache domain-containing protein 1; Cache domain containing 1
   
 
 0.683
PLXDC2
Plexin domain-containing protein 2 precursor; Bos taurus plexin domain containing 2 (PLXDC2), mRNA
   
  
 0.674
SCG5
Neuroendocrine protein 7b2 precursor; Bos taurus secretogranin V (7B2 protein) (SCG5), mRNA
   
  
 0.648
MDH1B
Putative malate dehydrogenase 1b; Bos taurus malate dehydrogenase 1B, NAD (soluble) (MDH1B), mRNA; Belongs to the LDH/MDH superfamily. MDH type 2 family
   
 
 0.632
UFC1
Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage
      
 0.625
WBP1L
Ww domain binding protein 1-like isoform x1; WW domain binding protein 1-like
      
 0.618
LRR1
Leucine-rich repeat protein 1; Bos taurus leucine rich repeat protein 1 (LRR1), mRNA
      
 0.609
CRBN
Protein cereblon; Substrate recognition component of a DCX (DDB1-CUL4-X- box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Normal degradation of key regulatory proteins is required for normal limb outgrowth and expression of the fibroblast growth factor FGF8 (By similarity). May play a role in memory and learning by regulating the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning via its interaction with KCNT1 (By sim [...]
      
 0.609
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, domestic cattle, domestic cow
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