node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALDH2 | AOC1 | ENSBTAP00000011521 | ENSBTAP00000007133 | Aldehyde dehydrogenase, mitochondrial; Belongs to the aldehyde dehydrogenase family. | Amine oxidase. | 0.933 |
ALDH2 | AOC2 | ENSBTAP00000011521 | ENSBTAP00000040444 | Aldehyde dehydrogenase, mitochondrial; Belongs to the aldehyde dehydrogenase family. | Amine oxidase. | 0.742 |
ALDH2 | AOC3 | ENSBTAP00000011521 | ENSBTAP00000047520 | Aldehyde dehydrogenase, mitochondrial; Belongs to the aldehyde dehydrogenase family. | Membrane primary amine oxidase; Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity (By similarity). | 0.772 |
ALDH2 | LOC100138645 | ENSBTAP00000011521 | ENSBTAP00000001383 | Aldehyde dehydrogenase, mitochondrial; Belongs to the aldehyde dehydrogenase family. | Amine oxidase. | 0.742 |
ALDH2 | MAOB | ENSBTAP00000011521 | ENSBTAP00000001698 | Aldehyde dehydrogenase, mitochondrial; Belongs to the aldehyde dehydrogenase family. | Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity); Belongs to the flavin monoamine oxidase family. | 0.951 |
ALDH3A1 | AOC2 | ENSBTAP00000028125 | ENSBTAP00000040444 | Aldehyde dehydrogenase, dimeric NADP-preferring; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids (By similarity). Preferentially oxidizes aromatic aldehyde substrates (By similarity). Comprises about 50 percent of corneal epithelial soluble proteins (By similarity). May play a role in preventing corneal damage caused by ultraviolet light (By similarity). | Amine oxidase. | 0.925 |
ALDH3A1 | AOC3 | ENSBTAP00000028125 | ENSBTAP00000047520 | Aldehyde dehydrogenase, dimeric NADP-preferring; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids (By similarity). Preferentially oxidizes aromatic aldehyde substrates (By similarity). Comprises about 50 percent of corneal epithelial soluble proteins (By similarity). May play a role in preventing corneal damage caused by ultraviolet light (By similarity). | Membrane primary amine oxidase; Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity (By similarity). | 0.928 |
ALDH3A1 | COMT | ENSBTAP00000028125 | ENSBTAP00000025997 | Aldehyde dehydrogenase, dimeric NADP-preferring; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids (By similarity). Preferentially oxidizes aromatic aldehyde substrates (By similarity). Comprises about 50 percent of corneal epithelial soluble proteins (By similarity). May play a role in preventing corneal damage caused by ultraviolet light (By similarity). | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | 0.934 |
ALDH3A1 | LOC100138645 | ENSBTAP00000028125 | ENSBTAP00000001383 | Aldehyde dehydrogenase, dimeric NADP-preferring; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids (By similarity). Preferentially oxidizes aromatic aldehyde substrates (By similarity). Comprises about 50 percent of corneal epithelial soluble proteins (By similarity). May play a role in preventing corneal damage caused by ultraviolet light (By similarity). | Amine oxidase. | 0.925 |
ALDH3A1 | MAOB | ENSBTAP00000028125 | ENSBTAP00000001698 | Aldehyde dehydrogenase, dimeric NADP-preferring; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids (By similarity). Preferentially oxidizes aromatic aldehyde substrates (By similarity). Comprises about 50 percent of corneal epithelial soluble proteins (By similarity). May play a role in preventing corneal damage caused by ultraviolet light (By similarity). | Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity); Belongs to the flavin monoamine oxidase family. | 0.951 |
ALDH3A1 | TOMT | ENSBTAP00000028125 | ENSBTAP00000003905 | Aldehyde dehydrogenase, dimeric NADP-preferring; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids (By similarity). Preferentially oxidizes aromatic aldehyde substrates (By similarity). Comprises about 50 percent of corneal epithelial soluble proteins (By similarity). May play a role in preventing corneal damage caused by ultraviolet light (By similarity). | Uncharacterized protein. | 0.917 |
AOC1 | ALDH2 | ENSBTAP00000007133 | ENSBTAP00000011521 | Amine oxidase. | Aldehyde dehydrogenase, mitochondrial; Belongs to the aldehyde dehydrogenase family. | 0.933 |
AOC1 | DDC | ENSBTAP00000007133 | ENSBTAP00000062111 | Amine oxidase. | Aromatic-L-amino-acid decarboxylase; Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine; Belongs to the group II decarboxylase family. | 0.920 |
AOC1 | MAOB | ENSBTAP00000007133 | ENSBTAP00000001698 | Amine oxidase. | Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity); Belongs to the flavin monoamine oxidase family. | 0.971 |
AOC2 | ALDH2 | ENSBTAP00000040444 | ENSBTAP00000011521 | Amine oxidase. | Aldehyde dehydrogenase, mitochondrial; Belongs to the aldehyde dehydrogenase family. | 0.742 |
AOC2 | ALDH3A1 | ENSBTAP00000040444 | ENSBTAP00000028125 | Amine oxidase. | Aldehyde dehydrogenase, dimeric NADP-preferring; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids (By similarity). Preferentially oxidizes aromatic aldehyde substrates (By similarity). Comprises about 50 percent of corneal epithelial soluble proteins (By similarity). May play a role in preventing corneal damage caused by ultraviolet light (By similarity). | 0.925 |
AOC2 | AOC3 | ENSBTAP00000040444 | ENSBTAP00000047520 | Amine oxidase. | Membrane primary amine oxidase; Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity (By similarity). | 0.904 |
AOC2 | COMT | ENSBTAP00000040444 | ENSBTAP00000025997 | Amine oxidase. | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | 0.900 |
AOC2 | DBH | ENSBTAP00000040444 | ENSBTAP00000047899 | Amine oxidase. | Soluble dopamine beta-hydroxylase; Conversion of dopamine to noradrenaline. Belongs to the copper type II ascorbate-dependent monooxygenase family. | 0.914 |
AOC2 | DDC | ENSBTAP00000040444 | ENSBTAP00000062111 | Amine oxidase. | Aromatic-L-amino-acid decarboxylase; Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine; Belongs to the group II decarboxylase family. | 0.908 |