| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GH1 | GHR | ENSBTAP00000022885 | ENSBTAP00000001758 | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues | Growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity); Belongs to the type I cytokine receptor family. Type 1 subfamily | 0.990 |
| GH1 | JAK2 | ENSBTAP00000022885 | ENSBTAP00000015986 | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues | Janus kinase 2 | 0.940 |
| GH1 | LYN | ENSBTAP00000022885 | ENSBTAP00000026686 | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues | LYN proto-oncogene, Src family tyrosine kinase | 0.900 |
| GH1 | MAPK3 | ENSBTAP00000022885 | ENSBTAP00000021507 | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues | Mitogen-activated protein kinase 3 | 0.910 |
| GH1 | PRL | ENSBTAP00000022885 | ENSBTAP00000020313 | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues | Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation | 0.955 |
| GH1 | PRLR | ENSBTAP00000022885 | ENSBTAP00000014437 | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues | Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin | 0.977 |
| GH1 | PRP1 | ENSBTAP00000022885 | ENSBTAP00000021026 | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues | Placental prolactin-related protein 1; Placental prolactin-related proteins may play a specific role during gestation | 0.945 |
| GH1 | PTPN1 | ENSBTAP00000022885 | ENSBTAP00000008678 | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues | Bos taurus protein tyrosine phosphatase, non-receptor type 1 (PTPN1), mRNA | 0.900 |
| GH1 | SH2B1 | ENSBTAP00000022885 | ENSBTAP00000025587 | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues | Bos taurus SH2B adaptor protein 1 (SH2B1), mRNA | 0.905 |
| GH1 | STAT5A | ENSBTAP00000022885 | ENSBTAP00000034715 | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues | Signal transducer and activator of transcription 5A; Carries out a dual function- signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation (By similarity) | 0.921 |
| GHR | GH1 | ENSBTAP00000001758 | ENSBTAP00000022885 | Growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity); Belongs to the type I cytokine receptor family. Type 1 subfamily | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues | 0.990 |
| GHR | JAK2 | ENSBTAP00000001758 | ENSBTAP00000015986 | Growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity); Belongs to the type I cytokine receptor family. Type 1 subfamily | Janus kinase 2 | 0.984 |
| GHR | LYN | ENSBTAP00000001758 | ENSBTAP00000026686 | Growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity); Belongs to the type I cytokine receptor family. Type 1 subfamily | LYN proto-oncogene, Src family tyrosine kinase | 0.909 |
| GHR | MAPK3 | ENSBTAP00000001758 | ENSBTAP00000021507 | Growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity); Belongs to the type I cytokine receptor family. Type 1 subfamily | Mitogen-activated protein kinase 3 | 0.906 |
| GHR | PRL | ENSBTAP00000001758 | ENSBTAP00000020313 | Growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity); Belongs to the type I cytokine receptor family. Type 1 subfamily | Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation | 0.966 |
| GHR | PRLR | ENSBTAP00000001758 | ENSBTAP00000014437 | Growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity); Belongs to the type I cytokine receptor family. Type 1 subfamily | Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin | 0.923 |
| GHR | PRP1 | ENSBTAP00000001758 | ENSBTAP00000021026 | Growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity); Belongs to the type I cytokine receptor family. Type 1 subfamily | Placental prolactin-related protein 1; Placental prolactin-related proteins may play a specific role during gestation | 0.918 |
| GHR | PTPN1 | ENSBTAP00000001758 | ENSBTAP00000008678 | Growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity); Belongs to the type I cytokine receptor family. Type 1 subfamily | Bos taurus protein tyrosine phosphatase, non-receptor type 1 (PTPN1), mRNA | 0.913 |
| GHR | SH2B1 | ENSBTAP00000001758 | ENSBTAP00000025587 | Growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity); Belongs to the type I cytokine receptor family. Type 1 subfamily | Bos taurus SH2B adaptor protein 1 (SH2B1), mRNA | 0.918 |
| GHR | STAT5A | ENSBTAP00000001758 | ENSBTAP00000034715 | Growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity); Belongs to the type I cytokine receptor family. Type 1 subfamily | Signal transducer and activator of transcription 5A; Carries out a dual function- signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation (By similarity) | 0.960 |
