Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TSKUTsukushi, small leucine rich proteoglycan. (344 aa)    
Predicted Functional Partners:
STOML1
Stomatin like 1.
   
 
 0.658
P2RY2
P2Y purinoceptor 2; Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system.
  
 
 
 0.631
ACER3
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
     
 0.590
ISY1
Uncharacterized protein.
    
 
 0.583
EPDR1
Mammalian ependymin-related protein 1; Binds anionic lipids and gangliosides at acidic pH. Belongs to the ependymin family.
      
 0.551
TBRG1
Transforming growth factor beta regulator 1.
      
 0.527
CLEC18C
MRCL protein.
      
 0.513
GDPD5
Glycerophosphodiester phosphodiesterase domain containing 5.
     
 0.504
HSPA13
Heat shock 70 kDa protein 13; Has peptide-independent ATPase activity.
    
 0.502
FBLN7
Fibulin 7.
    
 0.496
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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