| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CSF2 | CSF2RA-2 | ENSBTAP00000002054 | ENSBTAP00000067448 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | Fibronectin type-III domain-containing protein. | 0.994 |
| CSF2 | CSF2RB | ENSBTAP00000002054 | ENSBTAP00000011947 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | Colony stimulating factor 2 receptor beta common subunit. | 0.994 |
| CSF2 | IFNG | ENSBTAP00000002054 | ENSBTAP00000016634 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | 0.967 |
| CSF2 | IL1B | ENSBTAP00000002054 | ENSBTAP00000001745 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | 0.953 |
| CSF2 | IL3 | ENSBTAP00000002054 | ENSBTAP00000002774 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. | 0.996 |
| CSF2 | IL3RA | ENSBTAP00000002054 | ENSBTAP00000056952 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | Uncharacterized protein. | 0.977 |
| CSF2 | IL4 | ENSBTAP00000002054 | ENSBTAP00000021215 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] | 0.956 |
| CSF2 | IL5 | ENSBTAP00000002054 | ENSBTAP00000041739 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. | 0.995 |
| CSF2 | IL5RA | ENSBTAP00000002054 | ENSBTAP00000000339 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | Interleukin 5 receptor subunit alpha. | 0.969 |
| CSF2 | JAK2 | ENSBTAP00000002054 | ENSBTAP00000015986 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | Tyrosine-protein kinase. | 0.981 |
| CSF2RA-2 | CSF2 | ENSBTAP00000067448 | ENSBTAP00000002054 | Fibronectin type-III domain-containing protein. | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | 0.994 |
| CSF2RA-2 | CSF2RB | ENSBTAP00000067448 | ENSBTAP00000011947 | Fibronectin type-III domain-containing protein. | Colony stimulating factor 2 receptor beta common subunit. | 0.998 |
| CSF2RA-2 | IFNG | ENSBTAP00000067448 | ENSBTAP00000016634 | Fibronectin type-III domain-containing protein. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | 0.683 |
| CSF2RA-2 | IL3 | ENSBTAP00000067448 | ENSBTAP00000002774 | Fibronectin type-III domain-containing protein. | Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. | 0.935 |
| CSF2RA-2 | IL3RA | ENSBTAP00000067448 | ENSBTAP00000056952 | Fibronectin type-III domain-containing protein. | Uncharacterized protein. | 0.851 |
| CSF2RA-2 | IL4 | ENSBTAP00000067448 | ENSBTAP00000021215 | Fibronectin type-III domain-containing protein. | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] | 0.555 |
| CSF2RA-2 | IL5 | ENSBTAP00000067448 | ENSBTAP00000041739 | Fibronectin type-III domain-containing protein. | Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. | 0.855 |
| CSF2RA-2 | IL5RA | ENSBTAP00000067448 | ENSBTAP00000000339 | Fibronectin type-III domain-containing protein. | Interleukin 5 receptor subunit alpha. | 0.831 |
| CSF2RA-2 | JAK2 | ENSBTAP00000067448 | ENSBTAP00000015986 | Fibronectin type-III domain-containing protein. | Tyrosine-protein kinase. | 0.863 |
| CSF2RB | CSF2 | ENSBTAP00000011947 | ENSBTAP00000002054 | Colony stimulating factor 2 receptor beta common subunit. | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | 0.994 |
