node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADPGK | ALDOA | ENSBTAP00000002065 | ENSBTAP00000057869 | ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity); Belongs to the ADP-dependent glucokinase family. | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | 0.921 |
ADPGK | ALDOB | ENSBTAP00000002065 | ENSBTAP00000054283 | ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity); Belongs to the ADP-dependent glucokinase family. | Fructose-bisphosphate aldolase B. | 0.916 |
ADPGK | ALDOC | ENSBTAP00000002065 | ENSBTAP00000017416 | ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity); Belongs to the ADP-dependent glucokinase family. | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | 0.916 |
ADPGK | GALM | ENSBTAP00000002065 | ENSBTAP00000028111 | ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity); Belongs to the ADP-dependent glucokinase family. | Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity). | 0.921 |
ADPGK | GCK | ENSBTAP00000002065 | ENSBTAP00000043100 | ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity); Belongs to the ADP-dependent glucokinase family. | Phosphotransferase. | 0.944 |
ADPGK | GPI | ENSBTAP00000002065 | ENSBTAP00000073190 | ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity); Belongs to the ADP-dependent glucokinase family. | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). | 0.986 |
ADPGK | HK1 | ENSBTAP00000002065 | ENSBTAP00000063116 | ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity); Belongs to the ADP-dependent glucokinase family. | Hexokinase-1; Catalyzes the phosphorylation of various hexoses, such as D- glucose, D-glucosamine, D-fructose, D-mannose and 2-deoxy-D-glucose, to hexose 6-phosphate (D-glucose 6-phosphate, D-glucosamine 6-phosphate, D-fructose 6-phosphate, D-mannose 6-phosphate and 2-deoxy-D-glucose 6- phosphate, respectively). Does not phosphorylate N-acetyl-D-glucosamine (By similarity). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate (By similarity). Involved in innate immunity and inflammation by acting as a pattern recognition receptor f [...] | 0.942 |
ADPGK | HK2 | ENSBTAP00000002065 | ENSBTAP00000053231 | ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity); Belongs to the ADP-dependent glucokinase family. | Hexokinase 2. | 0.939 |
ADPGK | HKDC1 | ENSBTAP00000002065 | ENSBTAP00000044680 | ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity); Belongs to the ADP-dependent glucokinase family. | Hexokinase domain containing 1. | 0.942 |
ADPGK | PGM2 | ENSBTAP00000002065 | ENSBTAP00000007589 | ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity); Belongs to the ADP-dependent glucokinase family. | Phosphoglucomutase 2. | 0.956 |
ALDOA | ADPGK | ENSBTAP00000057869 | ENSBTAP00000002065 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity); Belongs to the ADP-dependent glucokinase family. | 0.921 |
ALDOA | ALDOB | ENSBTAP00000057869 | ENSBTAP00000054283 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Fructose-bisphosphate aldolase B. | 0.949 |
ALDOA | ALDOC | ENSBTAP00000057869 | ENSBTAP00000017416 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | 0.957 |
ALDOA | GCK | ENSBTAP00000057869 | ENSBTAP00000043100 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Phosphotransferase. | 0.883 |
ALDOA | GPI | ENSBTAP00000057869 | ENSBTAP00000073190 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). | 0.985 |
ALDOA | HK1 | ENSBTAP00000057869 | ENSBTAP00000063116 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Hexokinase-1; Catalyzes the phosphorylation of various hexoses, such as D- glucose, D-glucosamine, D-fructose, D-mannose and 2-deoxy-D-glucose, to hexose 6-phosphate (D-glucose 6-phosphate, D-glucosamine 6-phosphate, D-fructose 6-phosphate, D-mannose 6-phosphate and 2-deoxy-D-glucose 6- phosphate, respectively). Does not phosphorylate N-acetyl-D-glucosamine (By similarity). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate (By similarity). Involved in innate immunity and inflammation by acting as a pattern recognition receptor f [...] | 0.936 |
ALDOA | HK2 | ENSBTAP00000057869 | ENSBTAP00000053231 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Hexokinase 2. | 0.943 |
ALDOA | HKDC1 | ENSBTAP00000057869 | ENSBTAP00000044680 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Hexokinase domain containing 1. | 0.912 |
ALDOA | PGM2 | ENSBTAP00000057869 | ENSBTAP00000007589 | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Phosphoglucomutase 2. | 0.829 |
ALDOB | ADPGK | ENSBTAP00000054283 | ENSBTAP00000002065 | Fructose-bisphosphate aldolase B. | ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity); Belongs to the ADP-dependent glucokinase family. | 0.916 |