node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CALM-2 | ITPKA | ENSBTAP00000074130 | ENSBTAP00000002194 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Kinase; Belongs to the inositol phosphokinase (IPK) family. | 0.935 |
CALM-2 | ITPKB | ENSBTAP00000074130 | ENSBTAP00000058361 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Kinase; Belongs to the inositol phosphokinase (IPK) family. | 0.924 |
CALM-2 | ITPKC | ENSBTAP00000074130 | ENSBTAP00000025930 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Kinase; Belongs to the inositol phosphokinase (IPK) family. | 0.916 |
CALM-2 | PLCB1 | ENSBTAP00000074130 | ENSBTAP00000046644 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.936 |
INPP5A | INPP5J | ENSBTAP00000012098 | ENSBTAP00000022635 | Inositol polyphosphate-5-phosphatase A. | Inositol polyphosphate-5-phosphatase J. | 0.968 |
INPP5A | INPP5K | ENSBTAP00000012098 | ENSBTAP00000015257 | Inositol polyphosphate-5-phosphatase A. | Inositol polyphosphate-5-phosphatase K. | 0.930 |
INPP5A | IPMK | ENSBTAP00000012098 | ENSBTAP00000014872 | Inositol polyphosphate-5-phosphatase A. | Kinase; Belongs to the inositol phosphokinase (IPK) family. | 0.910 |
INPP5A | ITPK1 | ENSBTAP00000012098 | ENSBTAP00000042643 | Inositol polyphosphate-5-phosphatase A. | Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4. May also act as an isomerase that interconver [...] | 0.904 |
INPP5A | ITPKA | ENSBTAP00000012098 | ENSBTAP00000002194 | Inositol polyphosphate-5-phosphatase A. | Kinase; Belongs to the inositol phosphokinase (IPK) family. | 0.946 |
INPP5A | ITPKB | ENSBTAP00000012098 | ENSBTAP00000058361 | Inositol polyphosphate-5-phosphatase A. | Kinase; Belongs to the inositol phosphokinase (IPK) family. | 0.941 |
INPP5A | ITPKC | ENSBTAP00000012098 | ENSBTAP00000025930 | Inositol polyphosphate-5-phosphatase A. | Kinase; Belongs to the inositol phosphokinase (IPK) family. | 0.924 |
INPP5A | MINPP1 | ENSBTAP00000012098 | ENSBTAP00000007784 | Inositol polyphosphate-5-phosphatase A. | Multiple inositol-polyphosphate phosphatase 1; Belongs to the histidine acid phosphatase family. | 0.915 |
INPP5A | PLCB1 | ENSBTAP00000012098 | ENSBTAP00000046644 | Inositol polyphosphate-5-phosphatase A. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.915 |
INPP5J | INPP5A | ENSBTAP00000022635 | ENSBTAP00000012098 | Inositol polyphosphate-5-phosphatase J. | Inositol polyphosphate-5-phosphatase A. | 0.968 |
INPP5J | INPP5K | ENSBTAP00000022635 | ENSBTAP00000015257 | Inositol polyphosphate-5-phosphatase J. | Inositol polyphosphate-5-phosphatase K. | 0.906 |
INPP5J | IPMK | ENSBTAP00000022635 | ENSBTAP00000014872 | Inositol polyphosphate-5-phosphatase J. | Kinase; Belongs to the inositol phosphokinase (IPK) family. | 0.934 |
INPP5J | ITPK1 | ENSBTAP00000022635 | ENSBTAP00000042643 | Inositol polyphosphate-5-phosphatase J. | Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4. May also act as an isomerase that interconver [...] | 0.940 |
INPP5J | ITPKA | ENSBTAP00000022635 | ENSBTAP00000002194 | Inositol polyphosphate-5-phosphatase J. | Kinase; Belongs to the inositol phosphokinase (IPK) family. | 0.927 |
INPP5J | ITPKB | ENSBTAP00000022635 | ENSBTAP00000058361 | Inositol polyphosphate-5-phosphatase J. | Kinase; Belongs to the inositol phosphokinase (IPK) family. | 0.928 |
INPP5J | ITPKC | ENSBTAP00000022635 | ENSBTAP00000025930 | Inositol polyphosphate-5-phosphatase J. | Kinase; Belongs to the inositol phosphokinase (IPK) family. | 0.921 |