node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACLY | CS | ENSBTAP00000059914 | ENSBTAP00000005730 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | 0.996 |
ACLY | ENO1 | ENSBTAP00000059914 | ENSBTAP00000017839 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate (By similarity). In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons (By similarity). Stimulates immunoglobulin production (By similarity). | 0.631 |
ACLY | ENO2 | ENSBTAP00000059914 | ENSBTAP00000014978 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | ENO2 protein. | 0.513 |
ACLY | ENO3 | ENSBTAP00000059914 | ENSBTAP00000063298 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family. | 0.496 |
ACLY | MDH1 | ENSBTAP00000059914 | ENSBTAP00000069808 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Malate dehydrogenase, cytoplasmic. | 0.979 |
ACLY | MDH2 | ENSBTAP00000059914 | ENSBTAP00000012454 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Malate dehydrogenase, mitochondrial. | 0.980 |
ACLY | PC | ENSBTAP00000059914 | ENSBTAP00000069242 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Pyruvate carboxylase, mitochondrial; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate (By similarity). | 0.977 |
ACLY | PCK1 | ENSBTAP00000059914 | ENSBTAP00000069100 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Phosphoenolpyruvate carboxykinase, cytosolic [GTP]; Regulates cataplerosis and anaplerosis, the processes that control the levels of metabolic intermediates in the citric acid cycle. At low glucose levels, it catalyzes the cataplerotic conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. At high glucose levels, it catalyzes the anaplerotic conversion of phosphoenolpyruvate to oxaloacetate; Belongs to the phosphoenolpyruvate carboxykinase [...] | 0.964 |
ACLY | PKLR | ENSBTAP00000059914 | ENSBTAP00000061000 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.658 |
CS | ACLY | ENSBTAP00000005730 | ENSBTAP00000059914 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.996 |
CS | ENO1 | ENSBTAP00000005730 | ENSBTAP00000017839 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate (By similarity). In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons (By similarity). Stimulates immunoglobulin production (By similarity). | 0.512 |
CS | ENO2 | ENSBTAP00000005730 | ENSBTAP00000014978 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | ENO2 protein. | 0.578 |
CS | ENO3 | ENSBTAP00000005730 | ENSBTAP00000063298 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family. | 0.439 |
CS | MDH1 | ENSBTAP00000005730 | ENSBTAP00000069808 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Malate dehydrogenase, cytoplasmic. | 0.990 |
CS | MDH2 | ENSBTAP00000005730 | ENSBTAP00000012454 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Malate dehydrogenase, mitochondrial. | 0.998 |
CS | PC | ENSBTAP00000005730 | ENSBTAP00000069242 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Pyruvate carboxylase, mitochondrial; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate (By similarity). | 0.985 |
CS | PCK1 | ENSBTAP00000005730 | ENSBTAP00000069100 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Phosphoenolpyruvate carboxykinase, cytosolic [GTP]; Regulates cataplerosis and anaplerosis, the processes that control the levels of metabolic intermediates in the citric acid cycle. At low glucose levels, it catalyzes the cataplerotic conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. At high glucose levels, it catalyzes the anaplerotic conversion of phosphoenolpyruvate to oxaloacetate; Belongs to the phosphoenolpyruvate carboxykinase [...] | 0.957 |
CS | PKLR | ENSBTAP00000005730 | ENSBTAP00000061000 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.504 |
ENO1 | ACLY | ENSBTAP00000017839 | ENSBTAP00000059914 | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate (By similarity). In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons (By similarity). Stimulates immunoglobulin production (By similarity). | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.631 |
ENO1 | CS | ENSBTAP00000017839 | ENSBTAP00000005730 | Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate (By similarity). In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons (By similarity). Stimulates immunoglobulin production (By similarity). | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | 0.512 |