TGFB1I1 protein (Bos taurus) - STRING interaction network

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Your Current Organism:

Bos taurus

NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	TGFB1I1	ENSBTAP00000030053	ENSBTAP00000003094	Androgen receptor.	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. [...]	0.865
BCAR1	CRK	ENSBTAP00000073626	ENSBTAP00000007443	BCAR1 scaffold protein, Cas family member.	CRK proto-oncogene, adaptor protein.	0.999
BCAR1	PTK2	ENSBTAP00000073626	ENSBTAP00000065036	BCAR1 scaffold protein, Cas family member.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.998
BCAR1	PTK2B	ENSBTAP00000073626	ENSBTAP00000059391	BCAR1 scaffold protein, Cas family member.	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.993
BCAR1	TGFB1I1	ENSBTAP00000073626	ENSBTAP00000003094	BCAR1 scaffold protein, Cas family member.	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. [...]	0.864
BCAR1	VCL	ENSBTAP00000073626	ENSBTAP00000053644	BCAR1 scaffold protein, Cas family member.	Vinculin.	0.939
CRK	BCAR1	ENSBTAP00000007443	ENSBTAP00000073626	CRK proto-oncogene, adaptor protein.	BCAR1 scaffold protein, Cas family member.	0.999
CRK	ILK	ENSBTAP00000007443	ENSBTAP00000000927	CRK proto-oncogene, adaptor protein.	Integrin-linked protein kinase; Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.	0.479
CRK	PTK2	ENSBTAP00000007443	ENSBTAP00000065036	CRK proto-oncogene, adaptor protein.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.995
CRK	PTK2B	ENSBTAP00000007443	ENSBTAP00000059391	CRK proto-oncogene, adaptor protein.	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.978
CRK	TGFB1I1	ENSBTAP00000007443	ENSBTAP00000003094	CRK proto-oncogene, adaptor protein.	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. [...]	0.875
CRK	VCL	ENSBTAP00000007443	ENSBTAP00000053644	CRK proto-oncogene, adaptor protein.	Vinculin.	0.635
GIT1	PTK2	ENSBTAP00000069881	ENSBTAP00000065036	GIT ArfGAP 1.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.820
GIT1	PTK2B	ENSBTAP00000069881	ENSBTAP00000059391	GIT ArfGAP 1.	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.432
GIT1	TGFB1I1	ENSBTAP00000069881	ENSBTAP00000003094	GIT ArfGAP 1.	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. [...]	0.897
GIT1	VCL	ENSBTAP00000069881	ENSBTAP00000053644	GIT ArfGAP 1.	Vinculin.	0.482
ILK	CRK	ENSBTAP00000000927	ENSBTAP00000007443	Integrin-linked protein kinase; Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.	CRK proto-oncogene, adaptor protein.	0.479
ILK	PARVA	ENSBTAP00000000927	ENSBTAP00000061139	Integrin-linked protein kinase; Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.	Parvin alpha.	0.998
ILK	TGFB1I1	ENSBTAP00000000927	ENSBTAP00000003094	Integrin-linked protein kinase; Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. [...]	0.942
ILK	VCL	ENSBTAP00000000927	ENSBTAP00000053644	Integrin-linked protein kinase; Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.	Vinculin.	0.864

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