STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GLTPGlycolipid transfer protein; Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides; Belongs to the GLTP family (169 aa)    
Predicted Functional Partners:
GLTPD2
Glycolipid transfer protein domain containing 2
      
 0.811
GBA2
Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide to free glucose and ceramide
      
 0.673
MDH1
Malate dehydrogenase, cytoplasmic; Bos taurus malate dehydrogenase 1, NAD (soluble) (MDH1), mRNA
   
  
 0.672
GLTPD1
Ceramide-1-phosphate transfer protein; Mediates the intracellular transfer of ceramide-1- phosphate between organelle membranes and the cell membrane. Required for normal structure of the Golgi stacks. Can bind phosphoceramides with a variety of aliphatic chains, but has a preference for lipids with saturated C16:0 or monounsaturated C18:1 aliphatic chains, and is inefficient with phosphoceramides containing lignoceryl (C24:0). Plays a role in the regulation of the cellular levels of ceramide-1-phosphate, and thereby contributes to the regulation of phospholipase PLA2G4A activity and t [...]
   
  
 0.646
PLEKHA3
Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
      
 0.629
CPLX3
Complexin-3; Positively regulates a late step in synaptic vesicle exocytosis; Belongs to the complexin/synaphin family
      
 0.625
SLC2A13
Bos taurus solute carrier family 2 (facilitated glucose transporter), member 13 (SLC2A13), mRNA; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
   
  
 0.625
UGCG
Bos taurus UDP-glucose ceramide glucosyltransferase (UGCG), mRNA
      
 0.583
GDE1
Glycerophosphodiester phosphodiesterase 1; Has glycerophosphoinositol phosphodiesterase activity. Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Has little or no activity towards glycerophosphocholine. GDE1 activity can be modulated by G-protein signaling pathways (By similarity)
      
 0.556
NAIP
NLR family, apoptosis inhibitory protein
      
 0.551
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bos taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, domestic cattle, domestic cow
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