STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC22A1Solute carrier family 22 member 1; Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1- methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1- methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N- methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA recepto [...] (563 aa)    
Predicted Functional Partners:
SLC44A2
Choline transporter-like protein 2; Choline transporter; Belongs to the CTL (choline transporter-like) family.
   
 
 0.948
SLC44A4
Choline transporter-like protein 4; Choline transporter that plays a role in the choline- acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function of outer hair cells and the protection of hair cells from acoustic injury (By similarity). Also described as a thiamine pyrophosphate transporter in colon, may mediate the absorption of microbiota-generated thiamine pyrophosphate and contribute to host thiamine (vitamin B1) homeostasis (By similarity).
   
 
 0.941
SLC5A7
Solute carrier family 5 (Choline transporter), member 7; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
 
 0.936
SLC44A1
Solute carrier family 44 member 1; Belongs to the CTL (choline transporter-like) family.
   
 
 0.934
SLC44A3
Choline transporter-like protein 3.
   
 
 0.934
SLC22A4
Solute carrier family 22 member 4.
  
0.931
SLC22A5
Solute carrier family 22 (Organic cation/carnitine transporter), member 5.
  
0.930
SLC22A2
Solute carrier family 22 member 2.
  
 
0.913
SLC22A3
Solute carrier family 22 member 3.
  
  
0.912
SLC47A2
Multidrug and toxin extrusion protein; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
   
  
 0.697
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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