STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IFI27L2Interferon alpha-inducible protein 27-like protein 2; Plays a role in the apoptotic process and has a pro-apoptotic activity; Belongs to the IFI6/IFI27 family. (178 aa)    
Predicted Functional Partners:
DHX34
DExH-box helicase 34.
    
 
 0.616
LOC100336682
Fibrinogen C-terminal domain-containing protein.
    
 
 0.615
DDX52
Probable ATP-dependent RNA helicase DDX52; Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
      
 0.600
ITLN2-2
Fibrinogen C-terminal domain-containing protein.
    
 
 0.573
YIPF3
Yip1 domain family member 3.
   
  
 0.572
TINAGL1
Tubulointerstitial nephritis antigen like 1; Belongs to the peptidase C1 family.
    
 
 0.570
TMEM168
Transmembrane protein 168.
      
 0.552
OCEL1
Occludin_ELL domain-containing protein.
      
 0.530
UBE2B
Ubiquitin-conjugating enzyme E2 B; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys- 120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'- and 'Lys-63'-linked polyubiqui [...]
    
 
 0.528
ITLN2
Fibrinogen C-terminal domain-containing protein.
    
 
 0.509
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.