STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXO24F-box protein 24. (580 aa)    
Predicted Functional Partners:
CASKIN2
CASK interacting protein 2.
    
 
 0.696
NUB1
NEDD8 ultimate buster 1; Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8 and its conjugates to the proteasome for degradation (By similarity).
      
 0.668
MRPL12
39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family.
      
 0.648
RPL17
60S ribosomal protein L17; Belongs to the universal ribosomal protein uL22 family.
    
 
 0.644
PDRG1
P53 and DNA damage-regulated protein 1; May play a role in chaperone-mediated protein folding. Belongs to the prefoldin subunit beta family.
      
 0.617
LOC112445104
G protein-coupled receptor 101; Belongs to the G-protein coupled receptor 1 family.
      
 0.569
EIF2B2
Translation initiation factor eIF-2B subunit beta; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B alpha/beta/delta subunits family.
    
 
 0.542
GIT2
GIT ArfGAP 2.
    
 
 0.514
SSR4
Translocon-associated protein subunit delta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
      
 0.510
IQCN
Uncharacterized protein.
    
 
 0.483
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.