STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NNATNeuronatin; May participate in the maintenance of segment identity in the hindbrain and pituitary development, and maturation or maintenance of the overall structure of the nervous system. May function as a regulatory subunit of ion channels (By similarity); Belongs to the neuronatin family. (81 aa)    
Predicted Functional Partners:
BLCAP
Bladder cancer-associated protein; May regulate cell proliferation and coordinate apoptosis and cell cycle progression via a novel mechanism independent of both p53/TP53 and nuclear factor kappa B (NF-kappaB); Belongs to the BLCAP family.
   
  
 0.810
NAP1L5
Nucleosome assembly protein 1-like 5.
      
 0.783
PEG10
CCHC-type domain-containing protein.
      
 0.767
PLAGL1
PLAG1 like zinc finger 1.
   
  
 0.752
SGCE
Epsilon-sarcoglycan; Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
   
  
 0.748
MEST
Mesoderm-specific transcript homolog protein.
      
 0.742
SNRPN
Small nuclear ribonucleoprotein-associated protein N; May be involved in tissue-specific alternative RNA processing events; Belongs to the snRNP SmB/SmN family.
      
 0.740
NDN
Necdin, MAGE family member.
   
  
 0.704
IGF2R
Cation-independent mannose-6-phosphate receptor; Acts as a positive regulator of T-cell coactivation, by binding DPP4 (By similarity). Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2; Belongs to the MRL1/IGF2R family.
   
  
 0.691
GRB10
Growth factor receptor bound protein 10.
      
 0.688
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
Server load: medium (74%) [HD]