STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PELOProtein pelota homolog; Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity (Potential). Belongs to the eukaryotic release factor 1 family. Pelota subfamily. (386 aa)    
Predicted Functional Partners:
HBS1L
HBS1-like protein; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family.
   
 
 0.992
FAU
Ubiquitin-like protein FUBI.
    
 
 0.971
ENSBTAP00000061435
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
 
 0.971
ENSBTAP00000070171
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
 
 0.971
ABCE1
ATP binding cassette subfamily E member 1.
  
 
 0.936
RPS17
40S ribosomal protein S17; Belongs to the eukaryotic ribosomal protein eS17 family.
   
 
 0.873
RPS10
40S ribosomal protein S10; Component of the 40S ribosomal subunit.
    
 
 0.857
RPL19
60S ribosomal protein L19.
   
 
 0.848
RPL18
60S ribosomal protein L18.
    
 
 0.837
RPS9
40S ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family.
   
   0.835
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.