Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EHD4 | ENPP4 | ENSBTAP00000008933 | ENSBTAP00000004547 | EH domain containing 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | Bis(5'-adenosyl)-triphosphatase ENPP4; Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity); Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. | 0.602 |
| EHD4 | GNG13 | ENSBTAP00000008933 | ENSBTAP00000026313 | EH domain containing 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | G protein subunit gamma 13. | 0.537 |
| EHD4 | TUFT1 | ENSBTAP00000008933 | ENSBTAP00000043710 | EH domain containing 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | Tuftelin; Involved in the mineralization and structural organization of enamel. | 0.498 |
| ENPP4 | EHD4 | ENSBTAP00000004547 | ENSBTAP00000008933 | Bis(5'-adenosyl)-triphosphatase ENPP4; Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity); Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. | EH domain containing 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.602 |
| ENPP4 | FHIT | ENSBTAP00000004547 | ENSBTAP00000019177 | Bis(5'-adenosyl)-triphosphatase ENPP4; Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity); Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. | Bis(5'-adenosyl)-triphosphatase; Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival, such as CCND1 and BIRC5. Plays a role in the induction of apoptosis via SRC and AKT1 signaling pathways. Inhibits MDM2-mediated proteasomal degradation of p53/TP53 and thereby plays a role in p53/TP53-mediated apoptosi [...] | 0.904 |
| ENPP4 | FKBP7 | ENSBTAP00000004547 | ENSBTAP00000001452 | Bis(5'-adenosyl)-triphosphatase ENPP4; Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity); Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. | Peptidylprolyl isomerase. | 0.626 |
| ENPP4 | GNG13 | ENSBTAP00000004547 | ENSBTAP00000026313 | Bis(5'-adenosyl)-triphosphatase ENPP4; Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity); Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. | G protein subunit gamma 13. | 0.661 |
| ENPP4 | MFSD4A | ENSBTAP00000004547 | ENSBTAP00000006513 | Bis(5'-adenosyl)-triphosphatase ENPP4; Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity); Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. | Major facilitator superfamily domain containing 4A. | 0.687 |
| ENPP4 | NME8 | ENSBTAP00000004547 | ENSBTAP00000044371 | Bis(5'-adenosyl)-triphosphatase ENPP4; Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity); Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. | NME/NM23 family member 8. | 0.715 |
| ENPP4 | PDIA5 | ENSBTAP00000004547 | ENSBTAP00000025128 | Bis(5'-adenosyl)-triphosphatase ENPP4; Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity); Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. | Protein disulfide-isomerase A5; Belongs to the protein disulfide isomerase family. | 0.594 |
| ENPP4 | RCAN2 | ENSBTAP00000004547 | ENSBTAP00000048923 | Bis(5'-adenosyl)-triphosphatase ENPP4; Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity); Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. | Calcipressin-2; Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity). Belongs to the RCAN family. | 0.651 |
| ENPP4 | TMCC2 | ENSBTAP00000004547 | ENSBTAP00000003052 | Bis(5'-adenosyl)-triphosphatase ENPP4; Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity); Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. | Transmembrane and coiled-coil domain family 2. | 0.603 |
| ENPP4 | TUFT1 | ENSBTAP00000004547 | ENSBTAP00000043710 | Bis(5'-adenosyl)-triphosphatase ENPP4; Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity); Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. | Tuftelin; Involved in the mineralization and structural organization of enamel. | 0.599 |
| FHIT | ENPP4 | ENSBTAP00000019177 | ENSBTAP00000004547 | Bis(5'-adenosyl)-triphosphatase; Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival, such as CCND1 and BIRC5. Plays a role in the induction of apoptosis via SRC and AKT1 signaling pathways. Inhibits MDM2-mediated proteasomal degradation of p53/TP53 and thereby plays a role in p53/TP53-mediated apoptosi [...] | Bis(5'-adenosyl)-triphosphatase ENPP4; Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity); Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. | 0.904 |
| FKBP7 | ENPP4 | ENSBTAP00000001452 | ENSBTAP00000004547 | Peptidylprolyl isomerase. | Bis(5'-adenosyl)-triphosphatase ENPP4; Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity); Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. | 0.626 |
| FKBP7 | PDIA5 | ENSBTAP00000001452 | ENSBTAP00000025128 | Peptidylprolyl isomerase. | Protein disulfide-isomerase A5; Belongs to the protein disulfide isomerase family. | 0.544 |
| GNG13 | EHD4 | ENSBTAP00000026313 | ENSBTAP00000008933 | G protein subunit gamma 13. | EH domain containing 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.537 |
| GNG13 | ENPP4 | ENSBTAP00000026313 | ENSBTAP00000004547 | G protein subunit gamma 13. | Bis(5'-adenosyl)-triphosphatase ENPP4; Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity); Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. | 0.661 |
| GNG13 | TUFT1 | ENSBTAP00000026313 | ENSBTAP00000043710 | G protein subunit gamma 13. | Tuftelin; Involved in the mineralization and structural organization of enamel. | 0.507 |
| MFSD4A | ENPP4 | ENSBTAP00000006513 | ENSBTAP00000004547 | Major facilitator superfamily domain containing 4A. | Bis(5'-adenosyl)-triphosphatase ENPP4; Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity); Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. | 0.687 |
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