| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATF2 | ATF3 | ENSBTAP00000002963 | ENSBTAP00000011265 | Activating transcription factor 2. | Cyclic AMP-dependent transcription factor ATF-3; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter (By similarity). | 0.825 |
| ATF2 | FOS | ENSBTAP00000002963 | ENSBTAP00000005660 | Activating transcription factor 2. | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] | 0.938 |
| ATF2 | FOSB | ENSBTAP00000002963 | ENSBTAP00000010762 | Activating transcription factor 2. | FosB proto-oncogene, AP-1 transcription factor subunit. | 0.673 |
| ATF2 | FOSL1 | ENSBTAP00000002963 | ENSBTAP00000008136 | Activating transcription factor 2. | FOS like 1, AP-1 transcription factor subunit. | 0.850 |
| ATF2 | FOSL2 | ENSBTAP00000002963 | ENSBTAP00000032838 | Activating transcription factor 2. | FOS like 2, AP-1 transcription factor subunit. | 0.909 |
| ATF2 | JUN | ENSBTAP00000002963 | ENSBTAP00000005279 | Activating transcription factor 2. | Transcription factor AP-1; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28. Binds to the USP28 promoter; Belongs to the bZIP family. Jun subfamily. | 0.996 |
| ATF2 | JUNB | ENSBTAP00000002963 | ENSBTAP00000015987 | Activating transcription factor 2. | Transcription factor jun-B; Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3' (By similarity); Belongs to the bZIP family. Jun subfamily. | 0.941 |
| ATF2 | JUND | ENSBTAP00000002963 | ENSBTAP00000059607 | Activating transcription factor 2. | Transcription factor jun-D; Transcription factor binding AP-1 sites. Belongs to the bZIP family. Jun subfamily. | 0.781 |
| ATF2 | MAPK8 | ENSBTAP00000002963 | ENSBTAP00000073182 | Activating transcription factor 2. | Mitogen-activated protein kinase. | 0.926 |
| ATF2 | MAPK9 | ENSBTAP00000002963 | ENSBTAP00000061184 | Activating transcription factor 2. | Mitogen-activated protein kinase. | 0.973 |
| ATF3 | ATF2 | ENSBTAP00000011265 | ENSBTAP00000002963 | Cyclic AMP-dependent transcription factor ATF-3; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter (By similarity). | Activating transcription factor 2. | 0.825 |
| ATF3 | FOS | ENSBTAP00000011265 | ENSBTAP00000005660 | Cyclic AMP-dependent transcription factor ATF-3; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter (By similarity). | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] | 0.884 |
| ATF3 | FOSB | ENSBTAP00000011265 | ENSBTAP00000010762 | Cyclic AMP-dependent transcription factor ATF-3; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter (By similarity). | FosB proto-oncogene, AP-1 transcription factor subunit. | 0.625 |
| ATF3 | FOSL2 | ENSBTAP00000011265 | ENSBTAP00000032838 | Cyclic AMP-dependent transcription factor ATF-3; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter (By similarity). | FOS like 2, AP-1 transcription factor subunit. | 0.782 |
| ATF3 | JUN | ENSBTAP00000011265 | ENSBTAP00000005279 | Cyclic AMP-dependent transcription factor ATF-3; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter (By similarity). | Transcription factor AP-1; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28. Binds to the USP28 promoter; Belongs to the bZIP family. Jun subfamily. | 0.998 |
| ATF3 | JUNB | ENSBTAP00000011265 | ENSBTAP00000015987 | Cyclic AMP-dependent transcription factor ATF-3; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter (By similarity). | Transcription factor jun-B; Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3' (By similarity); Belongs to the bZIP family. Jun subfamily. | 0.927 |
| ATF3 | JUND | ENSBTAP00000011265 | ENSBTAP00000059607 | Cyclic AMP-dependent transcription factor ATF-3; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter (By similarity). | Transcription factor jun-D; Transcription factor binding AP-1 sites. Belongs to the bZIP family. Jun subfamily. | 0.905 |
| ATF3 | MAPK8 | ENSBTAP00000011265 | ENSBTAP00000073182 | Cyclic AMP-dependent transcription factor ATF-3; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter (By similarity). | Mitogen-activated protein kinase. | 0.729 |
| ATF3 | MAPK9 | ENSBTAP00000011265 | ENSBTAP00000061184 | Cyclic AMP-dependent transcription factor ATF-3; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter (By similarity). | Mitogen-activated protein kinase. | 0.721 |
| FOS | ATF2 | ENSBTAP00000005660 | ENSBTAP00000002963 | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] | Activating transcription factor 2. | 0.938 |
