STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF106Zinc finger protein 106. (1903 aa)    
Predicted Functional Partners:
USP14
Ubiquitin carboxyl-terminal hydrolase 14; Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibi [...]
   
    0.727
MYBBP1A
MYB binding protein 1a.
   
   0.723
AHCTF1
AT-hook containing transcription factor 1.
   
  
 0.699
PRRC2B
Proline rich coiled-coil 2B.
      
 0.687
SH3BP5
SH3 domain binding protein 5.
      
 0.674
EMSY
EMSY transcriptional repressor, BRCA2 interacting.
   
 
 0.666
USP24
Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family.
   
    0.659
HSPA4
Heat shock protein family A (Hsp70) member 4.
   
   0.628
PRRC2A
Proline rich coiled-coil 2A.
      
 0.622
KAZN-2
Uncharacterized protein.
      
 0.622
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.