| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBFB | FOXP3 | ENSBTAP00000021434 | ENSBTAP00000064761 | Core-binding factor subunit beta. | Forkhead box P3. | 0.672 |
| CBFB | GATA1 | ENSBTAP00000021434 | ENSBTAP00000004135 | Core-binding factor subunit beta. | GATA binding protein 1. | 0.684 |
| CBFB | HDAC1 | ENSBTAP00000021434 | ENSBTAP00000070647 | Core-binding factor subunit beta. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | 0.519 |
| CBFB | RUNX1 | ENSBTAP00000021434 | ENSBTAP00000006224 | Core-binding factor subunit beta. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.987 |
| CBFB | RUNX1T1 | ENSBTAP00000021434 | ENSBTAP00000072155 | Core-binding factor subunit beta. | RUNX1 translocation partner 1. | 0.584 |
| CSF1R | CSF2 | ENSBTAP00000016977 | ENSBTAP00000002054 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | 0.683 |
| CSF1R | FOXP3 | ENSBTAP00000016977 | ENSBTAP00000064761 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Forkhead box P3. | 0.537 |
| CSF1R | IL3 | ENSBTAP00000016977 | ENSBTAP00000002774 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. | 0.551 |
| CSF1R | RUNX1 | ENSBTAP00000016977 | ENSBTAP00000006224 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.963 |
| CSF1R | SPI1 | ENSBTAP00000016977 | ENSBTAP00000028937 | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Spi-1 proto-oncogene. | 0.977 |
| CSF2 | CSF1R | ENSBTAP00000002054 | ENSBTAP00000016977 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.683 |
| CSF2 | FOXP3 | ENSBTAP00000002054 | ENSBTAP00000064761 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | Forkhead box P3. | 0.776 |
| CSF2 | GATA1 | ENSBTAP00000002054 | ENSBTAP00000004135 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | GATA binding protein 1. | 0.419 |
| CSF2 | IL3 | ENSBTAP00000002054 | ENSBTAP00000002774 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. | 0.996 |
| CSF2 | RUNX1 | ENSBTAP00000002054 | ENSBTAP00000006224 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.950 |
| FOXP3 | CBFB | ENSBTAP00000064761 | ENSBTAP00000021434 | Forkhead box P3. | Core-binding factor subunit beta. | 0.672 |
| FOXP3 | CSF1R | ENSBTAP00000064761 | ENSBTAP00000016977 | Forkhead box P3. | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.537 |
| FOXP3 | CSF2 | ENSBTAP00000064761 | ENSBTAP00000002054 | Forkhead box P3. | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | 0.776 |
| FOXP3 | GATA1 | ENSBTAP00000064761 | ENSBTAP00000004135 | Forkhead box P3. | GATA binding protein 1. | 0.471 |
| FOXP3 | HDAC1 | ENSBTAP00000064761 | ENSBTAP00000070647 | Forkhead box P3. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | 0.638 |
