STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAMKVCaM kinase-like vesicle-associated. (504 aa)    
Predicted Functional Partners:
TMEM8B
Transmembrane protein 8B; May function as a regulator of the EGFR pathway. Probable tumor suppressor which may function in cell growth, proliferation and adhesion (By similarity); Belongs to the TMEM8 family.
      
 0.690
PRR14
Proline-rich protein 14; Functions in tethering peripheral heterochromatin to the nuclear lamina during interphase, possibly through the interaction with heterochromatin protein CBX5/HP1 alpha. Might play a role in reattaching heterochromatin to the nuclear lamina at mitotic exit. Promotes myoblast differentiation during skeletal myogenesis, possibly by stimulating transcription factor MyoD activity via binding to CBX5/HP1 alpha. Involved in the positive regulation of the PI3K-Akt- mTOR signaling pathway and in promoting cell proliferation, possibly via binding to GRB2 (By similarity).
      
 0.673
CDHR4
Cadherin related family member 4.
   
 
 0.635
PDZRN3
PDZ domain containing ring finger 3.
    
 
 0.598
MFAP3L
Microfibril associated protein 3 like.
      
 0.589
DCX
Doublecortin.
 
  
 
 0.544
DMRTA2
Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development; Belongs to the DMRT family.
      
 0.535
MON1A
Vacuolar fusion protein MON1 homolog A; Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes. Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form. Belongs to the MON1/SAND family.
   
  
 0.532
GRIK4
Glutamate ionotropic receptor kainate type subunit 4.
   
  
 0.513
ARHGAP23
Rho GTPase activating protein 23.
      
 0.510
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.