STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRATD1Protein LRATD1; May play a role in cell morphology and motility. Belongs to the LRATD family. (297 aa)    
Predicted Functional Partners:
DACT2
Dishevelled binding antagonist of beta catenin 2.
   
    0.797
ANKRD55
Ankyrin repeat domain 55.
      
 0.782
DOP1A
DOP1 leucine zipper like protein A.
      
 0.707
PPP1R1A
Protein phosphatase 1 regulatory inhibitor subunit 1A.
      
 0.687
KIAA0355
KIAA0355.
      
 0.681
BRS3
Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.
      
 0.661
LOC112445811
Bombesin receptor subtype-3.
      
 0.661
RESF1
Retroelement silencing factor 1.
      
 0.654
ZNF358
Zinc finger protein 358.
      
 0.622
RNF113A
E3 ubiquitin-protein ligase RNF113A; Required for pre-mRNA splicing as component of the spliceosome. E3 ubiquitin-protein ligase that catalyzes the transfer of ubiquitin onto target proteins. Catalyzes polyubiquitination of SNRNP200/BRR2 with non-canonical 'Lys-63'-linked polyubiquitin chains. Plays a role in DNA repair via its role in the synthesis of 'Lys-63'- linked polyubiquitin chains that recruit ALKBH3 and the ASCC complex to sites of DNA damage by alkylating agents. Ubiquitinates CXCR4, leading to its degradation, and thereby contributes to the termination of CXCR4 signaling.
      
 0.617
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.