node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BET1 | BET1L | ENSBTAP00000071456 | ENSBTAP00000057955 | Bet1 golgi vesicular membrane trafficking protein. | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity). | 0.903 |
BET1 | GOLGA2 | ENSBTAP00000071456 | ENSBTAP00000063838 | Bet1 golgi vesicular membrane trafficking protein. | Uncharacterized protein. | 0.585 |
BET1 | GOSR1 | ENSBTAP00000071456 | ENSBTAP00000006525 | Bet1 golgi vesicular membrane trafficking protein. | Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an import [...] | 0.997 |
BET1 | GOSR2 | ENSBTAP00000071456 | ENSBTAP00000069760 | Bet1 golgi vesicular membrane trafficking protein. | Uncharacterized protein; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | 0.998 |
BET1 | SCFD1 | ENSBTAP00000071456 | ENSBTAP00000043412 | Bet1 golgi vesicular membrane trafficking protein. | Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. | 0.996 |
BET1 | SEC22B | ENSBTAP00000071456 | ENSBTAP00000072245 | Bet1 golgi vesicular membrane trafficking protein. | SEC22 homolog B, vesicle trafficking protein; Belongs to the synaptobrevin family. | 0.993 |
BET1 | STX5 | ENSBTAP00000071456 | ENSBTAP00000043848 | Bet1 golgi vesicular membrane trafficking protein. | Syntaxin-5; Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter- connected structure of the Golgi apparatus. | 0.999 |
BET1 | USO1 | ENSBTAP00000071456 | ENSBTAP00000022642 | Bet1 golgi vesicular membrane trafficking protein. | General vesicular transport factor p115; General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity. | 0.968 |
BET1 | VAMP8 | ENSBTAP00000071456 | ENSBTAP00000032965 | Bet1 golgi vesicular membrane trafficking protein. | Vesicle-associated membrane protein 8; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t- SNARE complex. Also required for dense-granule secretion in platelets. Plays als [...] | 0.990 |
BET1 | YKT6 | ENSBTAP00000071456 | ENSBTAP00000000341 | Bet1 golgi vesicular membrane trafficking protein. | Synaptobrevin homolog YKT6; Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity; Belongs to the synaptobrevin family. | 0.999 |
BET1L | BET1 | ENSBTAP00000057955 | ENSBTAP00000071456 | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity). | Bet1 golgi vesicular membrane trafficking protein. | 0.903 |
BET1L | GOSR1 | ENSBTAP00000057955 | ENSBTAP00000006525 | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity). | Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an import [...] | 0.997 |
BET1L | GOSR2 | ENSBTAP00000057955 | ENSBTAP00000069760 | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity). | Uncharacterized protein; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | 0.989 |
BET1L | SCFD1 | ENSBTAP00000057955 | ENSBTAP00000043412 | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity). | Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. | 0.829 |
BET1L | SEC22B | ENSBTAP00000057955 | ENSBTAP00000072245 | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity). | SEC22 homolog B, vesicle trafficking protein; Belongs to the synaptobrevin family. | 0.871 |
BET1L | STX5 | ENSBTAP00000057955 | ENSBTAP00000043848 | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity). | Syntaxin-5; Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter- connected structure of the Golgi apparatus. | 0.997 |
BET1L | USO1 | ENSBTAP00000057955 | ENSBTAP00000022642 | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity). | General vesicular transport factor p115; General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity. | 0.955 |
BET1L | VAMP8 | ENSBTAP00000057955 | ENSBTAP00000032965 | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity). | Vesicle-associated membrane protein 8; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t- SNARE complex. Also required for dense-granule secretion in platelets. Plays als [...] | 0.780 |
BET1L | YKT6 | ENSBTAP00000057955 | ENSBTAP00000000341 | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity). | Synaptobrevin homolog YKT6; Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity; Belongs to the synaptobrevin family. | 0.992 |
GOLGA2 | BET1 | ENSBTAP00000063838 | ENSBTAP00000071456 | Uncharacterized protein. | Bet1 golgi vesicular membrane trafficking protein. | 0.585 |