STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C14H8orf82UPF0598 protein C8orf82 homolog; Belongs to the UPF0598 family. (229 aa)    
Predicted Functional Partners:
ARHGAP39
Rho GTPase activating protein 39.
 
    
 0.736
LRRC24
Leucine rich repeat containing 24.
   
  
 0.707
MFSD3
Major facilitator superfamily domain containing 3.
   
  
 0.684
MAF1
Repressor of RNA polymerase III transcription MAF1 homolog; Plays a role in the repression of RNA polymerase III-mediated transcription in response to changing nutritional, environmental and cellular stress conditions to balance the production of highly abundant tRNAs, 5S rRNA, and other small non-coding RNAs with cell growth and maintenance (By similarity). Plays also a key role in cell fate determination by promoting mesorderm induction and adipocyte differentiation (By similarity). Mechanistically, associates with the RNA polymerase III clamp and thereby impairs its recruitment to t [...]
   
  
 0.677
LRRC14
Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF-kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB.
   
  
 0.675
PPP1R16A
Protein phosphatase 1 regulatory subunit 16A.
   
  
 0.670
CYHR1
Cysteine and histidine-rich protein 1.
   
  
 0.669
GRINA
Protein lifeguard 1; Potential apoptotic regulator; Belongs to the BI1 family. LFG subfamily.
      
 0.661
C14H8orf33
UPF0488 protein C8orf33 homolog; Belongs to the UPF0488 family.
      
 0.658
KIFC2
Kinesin family member C2.
      
 0.655
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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