node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CYB5R2 | DPYD | ENSBTAP00000060361 | ENSBTAP00000007139 | Cytochrome b5 reductase 2. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. | 0.919 |
CYB5R2 | DPYS | ENSBTAP00000060361 | ENSBTAP00000029176 | Cytochrome b5 reductase 2. | Dihydropyrimidinase. | 0.604 |
CYB5R2 | UMPS | ENSBTAP00000060361 | ENSBTAP00000018248 | Cytochrome b5 reductase 2. | Orotidine 5'-phosphate decarboxylase; In the C-terminal section; belongs to the OMP decarboxylase family. | 0.884 |
CYB5R4 | DPYD | ENSBTAP00000067057 | ENSBTAP00000007139 | Cytochrome b5 reductase 4; NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS) (By similarity); Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. | 0.923 |
CYB5R4 | DPYS | ENSBTAP00000067057 | ENSBTAP00000029176 | Cytochrome b5 reductase 4; NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS) (By similarity); Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Dihydropyrimidinase. | 0.610 |
CYB5R4 | UMPS | ENSBTAP00000067057 | ENSBTAP00000018248 | Cytochrome b5 reductase 4; NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS) (By similarity); Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Orotidine 5'-phosphate decarboxylase; In the C-terminal section; belongs to the OMP decarboxylase family. | 0.912 |
DPYD | CYB5R2 | ENSBTAP00000007139 | ENSBTAP00000060361 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. | Cytochrome b5 reductase 2. | 0.919 |
DPYD | CYB5R4 | ENSBTAP00000007139 | ENSBTAP00000067057 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. | Cytochrome b5 reductase 4; NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS) (By similarity); Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.923 |
DPYD | DPYS | ENSBTAP00000007139 | ENSBTAP00000029176 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. | Dihydropyrimidinase. | 0.991 |
DPYD | OXNAD1 | ENSBTAP00000007139 | ENSBTAP00000006434 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. | Oxidoreductase NAD-binding domain-containing protein 1. | 0.913 |
DPYD | PNP | ENSBTAP00000007139 | ENSBTAP00000016346 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.945 |
DPYD | UMPS | ENSBTAP00000007139 | ENSBTAP00000018248 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. | Orotidine 5'-phosphate decarboxylase; In the C-terminal section; belongs to the OMP decarboxylase family. | 0.999 |
DPYD | UPB1 | ENSBTAP00000007139 | ENSBTAP00000069381 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. | Beta-ureidopropionase 1. | 0.964 |
DPYD | UPP1 | ENSBTAP00000007139 | ENSBTAP00000011088 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.986 |
DPYD | UPP2 | ENSBTAP00000007139 | ENSBTAP00000068146 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.981 |
DPYD | UPRT | ENSBTAP00000007139 | ENSBTAP00000005978 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. | Uracil phosphoribosyltransferase homolog. | 0.963 |
DPYS | CYB5R2 | ENSBTAP00000029176 | ENSBTAP00000060361 | Dihydropyrimidinase. | Cytochrome b5 reductase 2. | 0.604 |
DPYS | CYB5R4 | ENSBTAP00000029176 | ENSBTAP00000067057 | Dihydropyrimidinase. | Cytochrome b5 reductase 4; NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS) (By similarity); Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.610 |
DPYS | DPYD | ENSBTAP00000029176 | ENSBTAP00000007139 | Dihydropyrimidinase. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. | 0.991 |
DPYS | OXNAD1 | ENSBTAP00000029176 | ENSBTAP00000006434 | Dihydropyrimidinase. | Oxidoreductase NAD-binding domain-containing protein 1. | 0.604 |