STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
P4HTMProlyl 4-hydroxylase, transmembrane. (494 aa)    
Predicted Functional Partners:
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
   
 
 0.614
MTUS2
Microtubule associated scaffold protein 2.
      
 0.575
TARBP1
TAR (HIV-1) RNA binding protein 1.
      
 0.568
BPHL
Biphenyl hydrolase like.
      
 0.531
SDE2
SDE2 telomere maintenance homolog.
      
 0.527
RHBG
Ammonium transporter Rh type B; Functions as a specific ammonium transporter.
      
 0.502
P4HA3
Prolyl 4-hydroxylase subunit alpha-3; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
      
0.490
EVI2B
Ecotropic viral integration site 2B.
      
 0.486
SPCS1
Signal peptidase complex subunit 1; Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.
      
 0.486
KCNJ8
Potassium inwardly-rectifying channel, subfamily J, member 8.
      
 0.478
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.