STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEMA3CSemaphorin-3C; Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance (By similarity). (751 aa)    
Predicted Functional Partners:
NRP1
Neuropilin; Belongs to the neuropilin family.
  
 0.984
NRP2
Neuropilin; Belongs to the neuropilin family.
    
 
 0.895
PLXNA1
Plexin A1.
    
 
 0.879
PLXND1
Plexin D1.
    
 
0.878
PLXNA3
Plexin A3.
    
 
 0.809
PLXNA2
Plexin A2.
    
 
 0.761
PLXNB1
Plexin B1.
    
 
 0.706
PLXNA4
Plexin A4.
    
 
 0.661
NTN1
Netrin 1.
      
 0.643
PLXNB2
Plexin B2.
    
 
 0.637
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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