STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPR17G protein-coupled receptor 17; Belongs to the G-protein coupled receptor 1 family. (339 aa)    
Predicted Functional Partners:
OLIG2
Oligodendrocyte transcription factor 2.
      
 0.679
BCAS1
Breast carcinoma amplified sequence 1.
      
 0.638
MYRF
Myelin regulatory factor.
      
 0.628
GRK2
Beta-adrenergic receptor kinase 1; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation- independent manner (By similarity). Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity ; Belon [...]
    
 0.623
OLIG1
Oligodendrocyte transcription factor 1.
      
 0.618
GPR62
G protein-coupled receptor 62.
      
 0.617
SOX10
SRY-box transcription factor 10.
      
 0.609
PLP1
Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin.
      
 0.590
GPR37
G protein-coupled receptor 37 (Endothelin receptor type B-like).
      
 0.581
P2RY12
Purinergic receptor P2Y, G-protein coupled, 12.
     
0.561
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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