STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RBM5RNA-binding protein 5; Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate apoptosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes production of a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes production of a catalytically active form of CASP2/Cas [...] (815 aa)    
Predicted Functional Partners:
ZNF34
Zinc finger protein 34; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
   
   0.811
U2AF2
U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.
   
 
 0.808
NOL6
Nucleolar protein 6.
   
 
 0.806
SUGP1
SURP and G-patch domain containing 1.
   
 
0.778
DHX15
DEAH-box helicase 15.
   
 
 0.770
RBM39
RNA binding motif protein 39.
   
 
 0.708
ACIN1
Apoptotic chromatin condensation inducer 1.
   
  
 0.664
U2SURP
U2 snRNP associated SURP domain containing.
   
 
 0.656
PNISR
PNN interacting serine and arginine rich protein.
   
 
 0.642
DDX18
RNA helicase.
    
 
 0.638
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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