node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARPP19 | C8H9orf64 | ENSBTAP00000022929 | ENSBTAP00000008492 | cAMP-regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression (By similarity). | Queuosine salvage protein; Involved in salvaging queuosine. | 0.575 |
C8H9orf64 | ARPP19 | ENSBTAP00000008492 | ENSBTAP00000022929 | Queuosine salvage protein; Involved in salvaging queuosine. | cAMP-regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression (By similarity). | 0.575 |
C8H9orf64 | FILIP1L | ENSBTAP00000008492 | ENSBTAP00000018161 | Queuosine salvage protein; Involved in salvaging queuosine. | Filamin A interacting protein 1 like. | 0.564 |
C8H9orf64 | GK | ENSBTAP00000008492 | ENSBTAP00000062665 | Queuosine salvage protein; Involved in salvaging queuosine. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism; Belongs to the FGGY kinase family. | 0.567 |
C8H9orf64 | GK2 | ENSBTAP00000008492 | ENSBTAP00000043922 | Queuosine salvage protein; Involved in salvaging queuosine. | Uncharacterized protein; Belongs to the FGGY kinase family. | 0.567 |
C8H9orf64 | LOC538702 | ENSBTAP00000008492 | ENSBTAP00000049717 | Queuosine salvage protein; Involved in salvaging queuosine. | Glycerol kinase; Belongs to the FGGY kinase family. | 0.568 |
C8H9orf64 | MARCHF5 | ENSBTAP00000008492 | ENSBTAP00000027942 | Queuosine salvage protein; Involved in salvaging queuosine. | E3 ubiquitin-protein ligase MARCHF5; Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission. May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control. Promotes ubiquitination of FIS1, DNM1L and MFN1. | 0.627 |
C8H9orf64 | PGP | ENSBTAP00000008492 | ENSBTAP00000013127 | Queuosine salvage protein; Involved in salvaging queuosine. | Glycerol-3-phosphate phosphatase; Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3- phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear. In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP. | 0.652 |
C8H9orf64 | PKN2 | ENSBTAP00000008492 | ENSBTAP00000029201 | Queuosine salvage protein; Involved in salvaging queuosine. | Protein kinase N2. | 0.576 |
C8H9orf64 | RNF181 | ENSBTAP00000008492 | ENSBTAP00000024336 | Queuosine salvage protein; Involved in salvaging queuosine. | E3 ubiquitin-protein ligase RNF181; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | 0.690 |
C8H9orf64 | UCK2 | ENSBTAP00000008492 | ENSBTAP00000060894 | Queuosine salvage protein; Involved in salvaging queuosine. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.570 |
FILIP1L | C8H9orf64 | ENSBTAP00000018161 | ENSBTAP00000008492 | Filamin A interacting protein 1 like. | Queuosine salvage protein; Involved in salvaging queuosine. | 0.564 |
GK | C8H9orf64 | ENSBTAP00000062665 | ENSBTAP00000008492 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism; Belongs to the FGGY kinase family. | Queuosine salvage protein; Involved in salvaging queuosine. | 0.567 |
GK | GK2 | ENSBTAP00000062665 | ENSBTAP00000043922 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism; Belongs to the FGGY kinase family. | Uncharacterized protein; Belongs to the FGGY kinase family. | 0.405 |
GK | LOC538702 | ENSBTAP00000062665 | ENSBTAP00000049717 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism; Belongs to the FGGY kinase family. | Glycerol kinase; Belongs to the FGGY kinase family. | 0.404 |
GK | PGP | ENSBTAP00000062665 | ENSBTAP00000013127 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism; Belongs to the FGGY kinase family. | Glycerol-3-phosphate phosphatase; Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3- phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear. In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP. | 0.465 |
GK2 | C8H9orf64 | ENSBTAP00000043922 | ENSBTAP00000008492 | Uncharacterized protein; Belongs to the FGGY kinase family. | Queuosine salvage protein; Involved in salvaging queuosine. | 0.567 |
GK2 | GK | ENSBTAP00000043922 | ENSBTAP00000062665 | Uncharacterized protein; Belongs to the FGGY kinase family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism; Belongs to the FGGY kinase family. | 0.405 |
GK2 | LOC538702 | ENSBTAP00000043922 | ENSBTAP00000049717 | Uncharacterized protein; Belongs to the FGGY kinase family. | Glycerol kinase; Belongs to the FGGY kinase family. | 0.900 |
LOC538702 | C8H9orf64 | ENSBTAP00000049717 | ENSBTAP00000008492 | Glycerol kinase; Belongs to the FGGY kinase family. | Queuosine salvage protein; Involved in salvaging queuosine. | 0.568 |