STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXO8F-box only protein 8; May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential). (319 aa)    
Predicted Functional Partners:
CEP44
Centrosomal protein of 44 kDa.
      
 0.846
NMUR1
Neuromedin U receptor 1; Belongs to the G-protein coupled receptor 1 family.
      
 0.751
GLRA3
Glycine receptor alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.715
TBC1D12
TBC1 domain family member 12.
      
 0.709
TMEM64
Transmembrane protein 64.
      
 0.695
ARL1
ADP-ribosylation factor-like protein 1; GTP-binding protein. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus (By similarity).
   
 
 0.694
SKIDA1
SKI/DACH domain containing 1.
      
 0.681
EVI5
Ecotropic viral integration site 5.
      
 0.666
PSD
PH and SEC7 domain-containing protein 1; Guanine nucleotide exchange factor for ARF6 (By similarity). Induces cytoskeletal remodeling (By similarity).
      
 0.660
IL12RB1
Interleukin 12 receptor subunit beta 1.
      
 0.645
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.