| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKAP3 | CABYR | ENSBTAP00000001353 | ENSBTAP00000031584 | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. | Calcium binding tyrosine-(Y)-phosphorylation regulated. | 0.873 |
| AKAP3 | FSCB | ENSBTAP00000001353 | ENSBTAP00000050184 | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. | Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium. | 0.578 |
| AKAP3 | ODF2 | ENSBTAP00000001353 | ENSBTAP00000020325 | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. | Outer dense fiber protein 2; Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to th [...] | 0.490 |
| AKAP3 | ROPN1 | ENSBTAP00000001353 | ENSBTAP00000009113 | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. | Ropporin-1; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation. Belongs to the ropporin family. | 0.821 |
| AKAP3 | SPA17 | ENSBTAP00000001353 | ENSBTAP00000044793 | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. | Sperm surface protein Sp17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates. | 0.763 |
| AKAP3 | SPATA6 | ENSBTAP00000001353 | ENSBTAP00000004068 | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. | Spermatogenesis-associated protein 6; Required for formation of the sperm connecting piece during spermiogenesis. Sperm connecting piece is essential for linking the developing flagellum to the head during late spermiogenesis. May be involved in myosin-based microfilament transport through interaction with myosin subunits. | 0.532 |
| AKAP3 | TEKT4 | ENSBTAP00000001353 | ENSBTAP00000016726 | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. | Tektin-4; May be a structural component of the sperm flagellum. Contributes to normal sperm motility; Belongs to the tektin family. | 0.420 |
| AKAP3 | ZPBP | ENSBTAP00000001353 | ENSBTAP00000007229 | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. | Zona pellucida binding protein. | 0.554 |
| AKAP4 | CABYR | ENSBTAP00000042319 | ENSBTAP00000031584 | A-kinase anchoring protein 4. | Calcium binding tyrosine-(Y)-phosphorylation regulated. | 0.711 |
| AKAP4 | FSCB | ENSBTAP00000042319 | ENSBTAP00000050184 | A-kinase anchoring protein 4. | Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium. | 0.562 |
| AKAP4 | ODF2 | ENSBTAP00000042319 | ENSBTAP00000020325 | A-kinase anchoring protein 4. | Outer dense fiber protein 2; Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to th [...] | 0.585 |
| AKAP4 | ROPN1 | ENSBTAP00000042319 | ENSBTAP00000009113 | A-kinase anchoring protein 4. | Ropporin-1; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation. Belongs to the ropporin family. | 0.715 |
| AKAP4 | SPA17 | ENSBTAP00000042319 | ENSBTAP00000044793 | A-kinase anchoring protein 4. | Sperm surface protein Sp17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates. | 0.648 |
| AKAP4 | SPATA6 | ENSBTAP00000042319 | ENSBTAP00000004068 | A-kinase anchoring protein 4. | Spermatogenesis-associated protein 6; Required for formation of the sperm connecting piece during spermiogenesis. Sperm connecting piece is essential for linking the developing flagellum to the head during late spermiogenesis. May be involved in myosin-based microfilament transport through interaction with myosin subunits. | 0.541 |
| AKAP4 | TEKT4 | ENSBTAP00000042319 | ENSBTAP00000016726 | A-kinase anchoring protein 4. | Tektin-4; May be a structural component of the sperm flagellum. Contributes to normal sperm motility; Belongs to the tektin family. | 0.611 |
| CABYR | AKAP3 | ENSBTAP00000031584 | ENSBTAP00000001353 | Calcium binding tyrosine-(Y)-phosphorylation regulated. | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. | 0.873 |
| CABYR | AKAP4 | ENSBTAP00000031584 | ENSBTAP00000042319 | Calcium binding tyrosine-(Y)-phosphorylation regulated. | A-kinase anchoring protein 4. | 0.711 |
| CABYR | FSCB | ENSBTAP00000031584 | ENSBTAP00000050184 | Calcium binding tyrosine-(Y)-phosphorylation regulated. | Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium. | 0.739 |
| CABYR | ODF2 | ENSBTAP00000031584 | ENSBTAP00000020325 | Calcium binding tyrosine-(Y)-phosphorylation regulated. | Outer dense fiber protein 2; Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to th [...] | 0.642 |
| CABYR | ROPN1 | ENSBTAP00000031584 | ENSBTAP00000009113 | Calcium binding tyrosine-(Y)-phosphorylation regulated. | Ropporin-1; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation. Belongs to the ropporin family. | 0.783 |