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RARG protein (Bos taurus) - STRING interaction network
"RARG" - Bos taurus retinoic acid receptor, gamma in Bos taurus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RARGBos taurus retinoic acid receptor, gamma (RARG), mRNA (458 aa)    
Predicted Functional Partners:
RXRA
Uncharacterized protein; Retinoid X receptor, alpha (474 aa)
     
0.984
RXRB
Bos taurus retinoid X receptor, beta (RXRB), mRNA (532 aa)
     
0.980
RARA
Retinoic acid receptor, alpha (462 aa)
     
0.977
RXRG
Retinoic acid receptor RXR-gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5’-AGGTCA-3’ sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity); Belongs to the nuclear hormone receptor family. NR2 subfamily (463 aa)
     
0.970
CRABP2
Cellular retinoic acid-binding protein 2; Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors (By similarity) (138 aa)
     
  0.959
MED1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (1575 aa)
       
    0.944
RARB
Retinoic acid receptor, beta (446 aa)
         
0.902
NCOR1
Bos taurus nuclear receptor corepressor 1 (NCOR1), mRNA (2436 aa)
       
 
  0.834
NCOR2
Nuclear receptor corepressor 2 (2294 aa)
     
 
  0.815
NCOA1
Nuclear receptor coactivator 1 (1363 aa)
       
 
  0.796
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bos taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, domestic cattle, domestic cow
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