node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CSN1S1 | CSN1S2 | ENSBTAP00000010119 | ENSBTAP00000006590 | Antioxidant peptide; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | Alpha-S2-casein; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | 0.999 |
CSN1S1 | CSN2 | ENSBTAP00000010119 | ENSBTAP00000003409 | Antioxidant peptide; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | Antioxidant peptide; Important role in determination of the surface properties of the casein micelles. Casohypotensin acts as a bradykinin-potentiating peptide. Induces hypotension in rats. Acts as a strong competitive inhibitor of endo-oligopeptidase A. | 0.994 |
CSN1S1 | CSN3 | ENSBTAP00000010119 | ENSBTAP00000028685 | Antioxidant peptide; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | Casoplatelin; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk. Casoplatelin inhibits platelet aggregation; Belongs to the kappa-casein family. | 0.992 |
CSN1S1 | CYM | ENSBTAP00000010119 | ENSBTAP00000013970 | Antioxidant peptide; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | Chymosin; Chymosin is synthesized in the mucosa of the abomasum (fourth stomach) of young (unweaned) ruminants. The enzyme hydrolyzes casein to paracasein; Belongs to the peptidase A1 family. | 0.815 |
CSN1S1 | DGAT1 | ENSBTAP00000010119 | ENSBTAP00000037256 | Antioxidant peptide; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | Diacylglycerol O-acyltransferase 1; Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders. In liver, plays a role in esterifying exogenous fatty acids to glycerol. | 0.679 |
CSN1S1 | GH1 | ENSBTAP00000010119 | ENSBTAP00000061093 | Antioxidant peptide; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family. | 0.683 |
CSN1S1 | GLYCAM1 | ENSBTAP00000010119 | ENSBTAP00000017854 | Antioxidant peptide; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | Glycosylation-dependent cell adhesion molecule 1. | 0.883 |
CSN1S1 | LALBA | ENSBTAP00000010119 | ENSBTAP00000060771 | Antioxidant peptide; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family. | 0.990 |
CSN1S1 | LTF | ENSBTAP00000010119 | ENSBTAP00000001704 | Antioxidant peptide; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Lactoferricin B is an antimicrobial peptide. Inhibits the growth of Gram-negative and Gram-positive bacteria. | 0.784 |
CSN1S1 | PAEP | ENSBTAP00000010119 | ENSBTAP00000062602 | Antioxidant peptide; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | Beta-lactoglobulin; Primary component of whey, it binds retinol and is probably involved in the transport of that molecule; Belongs to the calycin superfamily. Lipocalin family. | 0.915 |
CSN1S2 | CSN1S1 | ENSBTAP00000006590 | ENSBTAP00000010119 | Alpha-S2-casein; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | Antioxidant peptide; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | 0.999 |
CSN1S2 | CSN2 | ENSBTAP00000006590 | ENSBTAP00000003409 | Alpha-S2-casein; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | Antioxidant peptide; Important role in determination of the surface properties of the casein micelles. Casohypotensin acts as a bradykinin-potentiating peptide. Induces hypotension in rats. Acts as a strong competitive inhibitor of endo-oligopeptidase A. | 0.973 |
CSN1S2 | CSN3 | ENSBTAP00000006590 | ENSBTAP00000028685 | Alpha-S2-casein; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | Casoplatelin; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk. Casoplatelin inhibits platelet aggregation; Belongs to the kappa-casein family. | 0.988 |
CSN1S2 | CYM | ENSBTAP00000006590 | ENSBTAP00000013970 | Alpha-S2-casein; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | Chymosin; Chymosin is synthesized in the mucosa of the abomasum (fourth stomach) of young (unweaned) ruminants. The enzyme hydrolyzes casein to paracasein; Belongs to the peptidase A1 family. | 0.716 |
CSN1S2 | DGAT1 | ENSBTAP00000006590 | ENSBTAP00000037256 | Alpha-S2-casein; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | Diacylglycerol O-acyltransferase 1; Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders. In liver, plays a role in esterifying exogenous fatty acids to glycerol. | 0.589 |
CSN1S2 | GH1 | ENSBTAP00000006590 | ENSBTAP00000061093 | Alpha-S2-casein; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family. | 0.678 |
CSN1S2 | GLYCAM1 | ENSBTAP00000006590 | ENSBTAP00000017854 | Alpha-S2-casein; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | Glycosylation-dependent cell adhesion molecule 1. | 0.967 |
CSN1S2 | LALBA | ENSBTAP00000006590 | ENSBTAP00000060771 | Alpha-S2-casein; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family. | 0.956 |
CSN1S2 | LTF | ENSBTAP00000006590 | ENSBTAP00000001704 | Alpha-S2-casein; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Lactoferricin B is an antimicrobial peptide. Inhibits the growth of Gram-negative and Gram-positive bacteria. | 0.750 |
CSN1S2 | PAEP | ENSBTAP00000006590 | ENSBTAP00000062602 | Alpha-S2-casein; Important role in the capacity of milk to transport calcium phosphate; Belongs to the alpha-casein family. | Beta-lactoglobulin; Primary component of whey, it binds retinol and is probably involved in the transport of that molecule; Belongs to the calycin superfamily. Lipocalin family. | 0.950 |