node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CADM4 | DRP2 | ENSBTAP00000021263 | ENSBTAP00000056839 | Cell adhesion molecule 4. | Dystrophin related protein 2. | 0.578 |
CADM4 | PRX | ENSBTAP00000021263 | ENSBTAP00000010183 | Cell adhesion molecule 4. | Periaxin; Scaffolding protein that functions as part of a dystroglycan complex in Schwann cells, and as part of EZR and AHNAK-containing complexes in eye lens fiber cells. Required for the maintenance of the peripheral myelin sheath that is essential for normal transmission of nerve impulses and normal perception of sensory stimuli. Required for normal transport of MBP mRNA from the perinuclear to the paranodal regions. Required for normal remyelination after nerve injury. Required for normal elongation of Schwann cells and normal length of the internodes between the nodes of Ranvier. [...] | 0.613 |
DRP2 | CADM4 | ENSBTAP00000056839 | ENSBTAP00000021263 | Dystrophin related protein 2. | Cell adhesion molecule 4. | 0.578 |
DRP2 | MPZ | ENSBTAP00000056839 | ENSBTAP00000045141 | Dystrophin related protein 2. | Myelin protein P0; Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction. | 0.431 |
DRP2 | PPL | ENSBTAP00000056839 | ENSBTAP00000002822 | Dystrophin related protein 2. | Periplakin. | 0.445 |
DRP2 | PRX | ENSBTAP00000056839 | ENSBTAP00000010183 | Dystrophin related protein 2. | Periaxin; Scaffolding protein that functions as part of a dystroglycan complex in Schwann cells, and as part of EZR and AHNAK-containing complexes in eye lens fiber cells. Required for the maintenance of the peripheral myelin sheath that is essential for normal transmission of nerve impulses and normal perception of sensory stimuli. Required for normal transport of MBP mRNA from the perinuclear to the paranodal regions. Required for normal remyelination after nerve injury. Required for normal elongation of Schwann cells and normal length of the internodes between the nodes of Ranvier. [...] | 0.881 |
EGR2 | GJB1 | ENSBTAP00000055288 | ENSBTAP00000027331 | Early growth response 2. | Gap junction beta-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | 0.607 |
EGR2 | MAG | ENSBTAP00000055288 | ENSBTAP00000049802 | Early growth response 2. | Myelin associated glycoprotein. | 0.485 |
EGR2 | MBP | ENSBTAP00000055288 | ENSBTAP00000074415 | Early growth response 2. | Myelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity). | 0.466 |
EGR2 | MPZ | ENSBTAP00000055288 | ENSBTAP00000045141 | Early growth response 2. | Myelin protein P0; Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction. | 0.812 |
EGR2 | PRX | ENSBTAP00000055288 | ENSBTAP00000010183 | Early growth response 2. | Periaxin; Scaffolding protein that functions as part of a dystroglycan complex in Schwann cells, and as part of EZR and AHNAK-containing complexes in eye lens fiber cells. Required for the maintenance of the peripheral myelin sheath that is essential for normal transmission of nerve impulses and normal perception of sensory stimuli. Required for normal transport of MBP mRNA from the perinuclear to the paranodal regions. Required for normal remyelination after nerve injury. Required for normal elongation of Schwann cells and normal length of the internodes between the nodes of Ranvier. [...] | 0.703 |
EZR | PPL | ENSBTAP00000059239 | ENSBTAP00000002822 | Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity). | Periplakin. | 0.910 |
EZR | PRX | ENSBTAP00000059239 | ENSBTAP00000010183 | Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity). | Periaxin; Scaffolding protein that functions as part of a dystroglycan complex in Schwann cells, and as part of EZR and AHNAK-containing complexes in eye lens fiber cells. Required for the maintenance of the peripheral myelin sheath that is essential for normal transmission of nerve impulses and normal perception of sensory stimuli. Required for normal transport of MBP mRNA from the perinuclear to the paranodal regions. Required for normal remyelination after nerve injury. Required for normal elongation of Schwann cells and normal length of the internodes between the nodes of Ranvier. [...] | 0.926 |
GJB1 | EGR2 | ENSBTAP00000027331 | ENSBTAP00000055288 | Gap junction beta-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Early growth response 2. | 0.607 |
GJB1 | MAG | ENSBTAP00000027331 | ENSBTAP00000049802 | Gap junction beta-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Myelin associated glycoprotein. | 0.526 |
GJB1 | MBP | ENSBTAP00000027331 | ENSBTAP00000074415 | Gap junction beta-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Myelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity). | 0.459 |
GJB1 | MPZ | ENSBTAP00000027331 | ENSBTAP00000045141 | Gap junction beta-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Myelin protein P0; Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction. | 0.695 |
GJB1 | PRX | ENSBTAP00000027331 | ENSBTAP00000010183 | Gap junction beta-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Periaxin; Scaffolding protein that functions as part of a dystroglycan complex in Schwann cells, and as part of EZR and AHNAK-containing complexes in eye lens fiber cells. Required for the maintenance of the peripheral myelin sheath that is essential for normal transmission of nerve impulses and normal perception of sensory stimuli. Required for normal transport of MBP mRNA from the perinuclear to the paranodal regions. Required for normal remyelination after nerve injury. Required for normal elongation of Schwann cells and normal length of the internodes between the nodes of Ranvier. [...] | 0.673 |
MAG | EGR2 | ENSBTAP00000049802 | ENSBTAP00000055288 | Myelin associated glycoprotein. | Early growth response 2. | 0.485 |
MAG | GJB1 | ENSBTAP00000049802 | ENSBTAP00000027331 | Myelin associated glycoprotein. | Gap junction beta-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | 0.526 |