node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATF2 | ATF4 | ENSBTAP00000002963 | ENSBTAP00000023213 | Activating transcription factor 2. | Cyclic AMP-dependent transcription factor ATF-4; Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to endoplasmic reticulum (ER) stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis [...] | 0.932 |
ATF2 | ATF6B | ENSBTAP00000002963 | ENSBTAP00000042742 | Activating transcription factor 2. | Activating transcription factor 6 beta. | 0.945 |
ATF2 | CAMK1 | ENSBTAP00000002963 | ENSBTAP00000010230 | Activating transcription factor 2. | Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. | 0.677 |
ATF2 | CREB1 | ENSBTAP00000002963 | ENSBTAP00000007201 | Activating transcription factor 2. | Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | 0.979 |
ATF2 | CREB5 | ENSBTAP00000002963 | ENSBTAP00000061067 | Activating transcription factor 2. | Uncharacterized protein. | 0.962 |
ATF4 | ATF2 | ENSBTAP00000023213 | ENSBTAP00000002963 | Cyclic AMP-dependent transcription factor ATF-4; Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to endoplasmic reticulum (ER) stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis [...] | Activating transcription factor 2. | 0.932 |
ATF4 | ATF6B | ENSBTAP00000023213 | ENSBTAP00000042742 | Cyclic AMP-dependent transcription factor ATF-4; Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to endoplasmic reticulum (ER) stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis [...] | Activating transcription factor 6 beta. | 0.929 |
ATF4 | CAMK1 | ENSBTAP00000023213 | ENSBTAP00000010230 | Cyclic AMP-dependent transcription factor ATF-4; Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to endoplasmic reticulum (ER) stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis [...] | Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. | 0.685 |
ATF4 | CREB1 | ENSBTAP00000023213 | ENSBTAP00000007201 | Cyclic AMP-dependent transcription factor ATF-4; Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to endoplasmic reticulum (ER) stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis [...] | Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | 0.963 |
ATF4 | CREB5 | ENSBTAP00000023213 | ENSBTAP00000061067 | Cyclic AMP-dependent transcription factor ATF-4; Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to endoplasmic reticulum (ER) stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis [...] | Uncharacterized protein. | 0.926 |
ATF6B | ATF2 | ENSBTAP00000042742 | ENSBTAP00000002963 | Activating transcription factor 6 beta. | Activating transcription factor 2. | 0.945 |
ATF6B | ATF4 | ENSBTAP00000042742 | ENSBTAP00000023213 | Activating transcription factor 6 beta. | Cyclic AMP-dependent transcription factor ATF-4; Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to endoplasmic reticulum (ER) stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis [...] | 0.929 |
ATF6B | CAMK1 | ENSBTAP00000042742 | ENSBTAP00000010230 | Activating transcription factor 6 beta. | Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. | 0.671 |
ATF6B | CREB1 | ENSBTAP00000042742 | ENSBTAP00000007201 | Activating transcription factor 6 beta. | Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | 0.924 |
ATF6B | CREB5 | ENSBTAP00000042742 | ENSBTAP00000061067 | Activating transcription factor 6 beta. | Uncharacterized protein. | 0.907 |
CALM-2 | CALM3 | ENSBTAP00000074130 | ENSBTAP00000019411 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Uncharacterized protein; Belongs to the calmodulin family. | 0.970 |
CALM-2 | CALML4 | ENSBTAP00000074130 | ENSBTAP00000036380 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Calmodulin-like protein 4; Belongs to the calmodulin family. | 0.973 |
CALM-2 | CALML5 | ENSBTAP00000074130 | ENSBTAP00000018403 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Calmodulin like 5. | 0.971 |
CALM-2 | CAMK1 | ENSBTAP00000074130 | ENSBTAP00000010230 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. | 0.886 |
CALM-2 | CREB1 | ENSBTAP00000074130 | ENSBTAP00000007201 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). | Cyclic AMP-responsive element-binding protein 1; Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. | 0.762 |