node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NCOA1 | NCOR1 | ENSBTAP00000055281 | ENSBTAP00000053758 | Nuclear receptor coactivator. | Nuclear receptor corepressor 1. | 0.833 |
NCOA1 | NCOR2 | ENSBTAP00000055281 | ENSBTAP00000060821 | Nuclear receptor coactivator. | Nuclear receptor corepressor 2. | 0.805 |
NCOA1 | PPARA | ENSBTAP00000055281 | ENSBTAP00000010606 | Nuclear receptor coactivator. | Peroxisome proliferative activated receptor, alpha isoform 1. | 0.963 |
NCOA1 | PPARGC1A | ENSBTAP00000055281 | ENSBTAP00000022636 | Nuclear receptor coactivator. | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. Induces the expression of PERM1 in [...] | 0.654 |
NCOA1 | RXRA | ENSBTAP00000055281 | ENSBTAP00000023729 | Nuclear receptor coactivator. | Retinoid X receptor alpha. | 0.965 |
NCOA1 | RXRB | ENSBTAP00000055281 | ENSBTAP00000000860 | Nuclear receptor coactivator. | Retinoid X receptor, beta. | 0.847 |
NCOA1 | RXRG | ENSBTAP00000055281 | ENSBTAP00000022350 | Nuclear receptor coactivator. | Retinoic acid receptor RXR-gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity). | 0.917 |
NCOR1 | NCOA1 | ENSBTAP00000053758 | ENSBTAP00000055281 | Nuclear receptor corepressor 1. | Nuclear receptor coactivator. | 0.833 |
NCOR1 | NCOR2 | ENSBTAP00000053758 | ENSBTAP00000060821 | Nuclear receptor corepressor 1. | Nuclear receptor corepressor 2. | 0.961 |
NCOR1 | PPARA | ENSBTAP00000053758 | ENSBTAP00000010606 | Nuclear receptor corepressor 1. | Peroxisome proliferative activated receptor, alpha isoform 1. | 0.902 |
NCOR1 | PPARGC1A | ENSBTAP00000053758 | ENSBTAP00000022636 | Nuclear receptor corepressor 1. | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. Induces the expression of PERM1 in [...] | 0.510 |
NCOR1 | RXRA | ENSBTAP00000053758 | ENSBTAP00000023729 | Nuclear receptor corepressor 1. | Retinoid X receptor alpha. | 0.910 |
NCOR1 | RXRB | ENSBTAP00000053758 | ENSBTAP00000000860 | Nuclear receptor corepressor 1. | Retinoid X receptor, beta. | 0.869 |
NCOR1 | RXRG | ENSBTAP00000053758 | ENSBTAP00000022350 | Nuclear receptor corepressor 1. | Retinoic acid receptor RXR-gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity). | 0.869 |
NCOR2 | NCOA1 | ENSBTAP00000060821 | ENSBTAP00000055281 | Nuclear receptor corepressor 2. | Nuclear receptor coactivator. | 0.805 |
NCOR2 | NCOR1 | ENSBTAP00000060821 | ENSBTAP00000053758 | Nuclear receptor corepressor 2. | Nuclear receptor corepressor 1. | 0.961 |
NCOR2 | PPARA | ENSBTAP00000060821 | ENSBTAP00000010606 | Nuclear receptor corepressor 2. | Peroxisome proliferative activated receptor, alpha isoform 1. | 0.945 |
NCOR2 | RXRA | ENSBTAP00000060821 | ENSBTAP00000023729 | Nuclear receptor corepressor 2. | Retinoid X receptor alpha. | 0.897 |
NCOR2 | RXRB | ENSBTAP00000060821 | ENSBTAP00000000860 | Nuclear receptor corepressor 2. | Retinoid X receptor, beta. | 0.813 |
NCOR2 | RXRG | ENSBTAP00000060821 | ENSBTAP00000022350 | Nuclear receptor corepressor 2. | Retinoic acid receptor RXR-gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity). | 0.821 |