STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RGL3Ral guanine nucleotide dissociation stimulator like 3. (727 aa)    
Predicted Functional Partners:
RALB
V-ral simian leukemia viral oncogene homolog B.
   
 
 0.826
HRAS
HRas proto-oncogene, GTPase.
   
 0.778
NRAS
NRAS proto-oncogene, GTPase.
   
 0.773
KRAS
KRAS proto-oncogene, GTPase.
   
 0.757
RALA
V-ral simian leukemia viral oncogene homolog A (Ras related).
   
 
 0.712
RALGAPB
Ral GTPase activating protein non-catalytic beta subunit.
      
 0.670
RALGAPA1
Ral GTPase activating protein catalytic alpha subunit 1.
      
 0.662
RALGAPA2
Ral GTPase activating protein catalytic alpha subunit 2.
      
 0.657
ARAF
Metalloproteinase inhibitor 1; Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling.
    
 
 0.572
RIN1
Ras and Rab interactor 1.
    
 
 0.566
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.